Tolderlund K, Bentzon M W, Bunch-Christensen K, Mackeprang B, Guld J, Waaler H
Bull World Health Organ. 1967;36(5):747-58.
It has been traditional practice in many countries to let revaccination with BCG depend on the outcome of periodically repeated tuberculin testing. Acquired resistance to tuberculosis and tuberculin skin sensitivity are concomitant results of BCG vaccination, and it is apparently inferred that a waning resistance will be faithfully reflected in a waning tuberculin sensitivity. However, it has been demonstrated in recent years, both in man and in animals, that the waning of tuberculin sensitivity may be prevented merely by a repetition of the tuberculin test, while data presented in this and a following report indicate that tuberculin testing has no such influence on the course of BCG-induced resistance to tuberculosis.
在许多国家,传统做法是让卡介苗复种取决于定期重复进行的结核菌素试验结果。对结核病的获得性抵抗力和结核菌素皮肤敏感性是卡介苗接种的伴随结果,显然据此推断,抵抗力的减弱将如实地反映在结核菌素敏感性的减弱上。然而,近年来在人和动物身上均已证明,仅仅通过重复结核菌素试验就可以防止结核菌素敏感性的减弱,而本报告及后续报告中提供的数据表明,结核菌素试验对卡介苗诱导的抗结核抵抗力的进程没有这种影响。