Mulla M S
Bull World Health Organ. 1967;37(2):311-5.
It is generally agreed that no single approach can solve the Culex pipiens fatigans problem at present. The use of larvicides must be integrated and co-ordinated with control techniques utilizing sanitary measures and, in suitable habitats, the use of predacious fish.In the testing of larvicides, factors such as mammalian toxicity and the persistence of toxic residues are important. Organochlorine larvicides persist and accumulate in food-chain organisms, but organophosphorus compounds readily degrade in most plant and animal tissues. In studying these factors a distinction should be made between the laboratory toxicity of a compound and its hazards under field conditions. The development of acquired resistance is a further factor influencing the search for new insecticides.The successful suppression of C. p. fatigans by larvicides will greatly depend on the use of suitable formulations, e.g., solid ones in pit latrines and septic tanks and dense liquid formulations in pukka and kutcha drains. Granular formulations have numerous advantages and their use should be further explored.
目前普遍认为,没有单一的方法能够解决致倦库蚊问题。杀幼虫剂的使用必须与利用卫生措施的控制技术相结合并协调起来,在合适的栖息地还要与捕食性鱼类的使用相结合。在测试杀幼虫剂时,诸如对哺乳动物的毒性和有毒残留物的持久性等因素很重要。有机氯杀幼虫剂会在食物链生物中持续存在并积累,但有机磷化合物在大多数动植物组织中很容易降解。在研究这些因素时,应该区分化合物在实验室中的毒性及其在野外条件下的危害。获得性抗性的发展是影响新型杀虫剂研发的另一个因素。通过杀幼虫剂成功抑制致倦库蚊将很大程度上取决于合适剂型的使用,例如,在坑式厕所和化粪池中使用固体剂型,在永久性和临时性排水系统中使用浓缩液体制剂。颗粒剂有很多优点,应该进一步探索其用途。