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异狄氏剂食物中毒。关于两批分别受异狄氏剂污染的面粉引发的四起疫情的报告。

Endrin food-poisoning. A report on four outbreaks caused by two separate shipments of endrin-contaminated flour.

作者信息

Weeks D E

出版信息

Bull World Health Organ. 1967;37(4):499-512.

PMID:5301732
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2554356/
Abstract

Between 3 June and 15 July 1967 four explosive outbreaks of acute poisoning with the insecticide endrin occurred in Doha in Qatar and Hofuf in Saudi Arabia. Altogether 874 persons were hospitalized and 26 died. It is estimated that many others were poisoned whose symptoms were not so severe as to cause them to seek medical care or to enter hospital.The author describes the course of the outbreaks and the measures taken to ascertain their cause and prevent their extension and recurrence. It was found that the victims had eaten bread made from flour contaminated with endrin. In two different ships, both of them loaded and off-loaded at different ports, flour and endrin had been stowed in the same hold, with the endrin above the flour. In both ships the endrin containers had leaked and penetrated the sacks of flour which was later used to make bread.These two unconnected but nearly simultaneous mass poisonings emphasize the importance of regulating the carriage of insecticides and other toxic chemicals in such a way as to prevent the contamination of foodstuffs and similar substances during transport; both the World Health Organization and the Inter-Governmental Maritime Consultative Organization are working towards the establishment of regulations and practices to that end.

摘要

1967年6月3日至7月15日期间,卡塔尔多哈和沙特阿拉伯胡富夫发生了四起因杀虫剂异狄氏剂导致的急性中毒爆发事件。共有874人住院,26人死亡。据估计,还有许多中毒者症状较轻,未寻求医疗救治或住院治疗。作者描述了疫情的发展过程以及为查明病因、防止疫情蔓延和复发所采取的措施。发现受害者食用了用被异狄氏剂污染的面粉制作的面包。在两艘不同的船上,这两艘船在不同港口装卸货物,面粉和异狄氏剂被存放在同一货舱,异狄氏剂在面粉上方。两艘船上的异狄氏剂容器都发生了泄漏,渗入了面粉袋,这些面粉后来被用来制作面包。这两起没有关联但几乎同时发生的大规模中毒事件凸显了规范杀虫剂和其他有毒化学品运输的重要性,以防止在运输过程中食品和类似物质受到污染;世界卫生组织和政府间海事协商组织都在努力为此制定相关规定和做法。

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本文引用的文献

1
Parathion poisoning from contaminated barley.受污染大麦导致的对硫磷中毒
Lancet. 1960 Mar 5;1(7123):538-42. doi: 10.1016/s0140-6736(60)90466-9.
2
AN ULTRAMICRO SCREENING METHOD FOR THE DETERMINATION OF BLOOD CHOLINESTERASE.一种测定血液胆碱酯酶的超微量筛选方法。
J Occup Med. 1965 Jul;7:303-13. doi: 10.1097/00043764-196507000-00001.
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PARATHION POISONING FROM FLANNELETTE SHEETS.平纹细布床单导致的对硫磷中毒
Can Med Assoc J. 1965 Apr 10;92(15):809-13.
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Clothing-borne epidemic. Organic phosphate poisoning in children.
JAMA. 1963 Apr 27;184:266-8. doi: 10.1001/jama.1963.03700170058008.
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The Kerala food poisoning.喀拉拉邦食物中毒事件
J Indian Med Assoc. 1958 Sep 1;31(5):204-7.
6
Outbreak of food-poisoning from bread made of chemically contaminated flour.由化学污染面粉制成的面包引发的食物中毒事件。
Br Med J. 1956 Aug 18;2(4989):393-8. doi: 10.1136/bmj.2.4989.393.
7
Acute endrin poisoning.急性异狄氏剂中毒
JAMA. 1967 Nov 6;202(6):489-93.