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巴基斯坦因安特灵中毒引发的惊厥。

Convulsions caused by endrin poisoning in Pakistan.

作者信息

Rowley D L, Rab M A, Hardjotanojo W, Liddle J, Burse V W, Saleem M, Sokal D, Falk H, Head S L

出版信息

Pediatrics. 1987 Jun;79(6):928-34.

PMID:3588147
Abstract

From July through September 1984, acute convulsions caused by endrin poisoning occurred in the subdistrict of Talagang, Attock District, Punjab province, Pakistan. Eighteen of the 21 affected villages were surveyed; 70% of the cases for which ages were known (106 of 152) were in children 1 to 9 years of age; 9.8% of all affected persons (19 of 194) died. The outbreak occurred in villages on the main roads of the subdistrict and peaked in early September. Endrin was detected in the blood of 12 of 18 patients with a history of convulsions but was not found in the blood of four hospitalized control patients. One composite sugar sample taken from the homes of three persons had an endrin level of 0.04 ppm. Because of the high toxicity, repeated association with large-scale outbreaks of neurologic illness, and the difficulties of monitoring distribution, endrin should not be used for agricultural purposes.

摘要

1984年7月至9月期间,巴基斯坦旁遮普省阿托克县塔拉冈分区发生了因安特灵中毒导致的急性惊厥事件。对21个受灾村庄中的18个进行了调查;已知年龄的病例中70%(152例中的106例)为1至9岁的儿童;所有受灾人员中有9.8%(194例中的19例)死亡。疫情发生在该分区主要道路沿线的村庄,并于9月初达到高峰。18例有惊厥病史的患者中有12例血液中检测出安特灵,但4例住院对照患者的血液中未检测到。从三人家庭采集的一份复合糖样本中,安特灵含量为0.04 ppm。由于毒性高、多次与大规模神经系统疾病暴发相关联以及监测其分布存在困难,安特灵不应再用于农业目的。

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Convulsions caused by endrin poisoning in Pakistan.巴基斯坦因安特灵中毒引发的惊厥。
Pediatrics. 1987 Jun;79(6):928-34.
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Leads from the MMWR. Acute convulsions associated with endrin poisoning--Pakistan.《发病率与死亡率周报》简讯。巴基斯坦与安特灵中毒相关的急性惊厥。
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Seizures after eating a snack food contaminated with the pesticide endrin. The tale of the toxic taquitos.食用被杀虫剂异狄氏剂污染的休闲食品后引发的癫痫。有毒玉米卷饼的故事。
West J Med. 1992 Dec;157(6):648-51.