O-（β-羟乙基）芦丁对大鼠伤口愈合的影响。
Effect of O-(beta-hydroxyethyl)-rutoside on wound healing in the rat.
作者信息
Wilhelmi G
出版信息
Pharmacology. 1979;19(2):82-5. doi: 10.1159/000137292.
PMID:531085
Abstract
The administration of O-(beta-hydroxyethyl)-rutoside in 11 daily doses of 300--400 mg/kg p.o. stimulates wound healing by granulation in the rat. The preparation may counteract the inhibitory effect of prednisone on the formation of granulation tissue. In five doses of 300--1,000 mg/kg daily p.o. it augments the tensile strength of cicatricial tissue to a statistically significant degree.
摘要
口服给予大鼠11日剂量、每日300 - 400 mg/kg的O-(β-羟乙基)-芦丁，可刺激大鼠通过肉芽组织促进伤口愈合。该制剂可抵消泼尼松对肉芽组织形成的抑制作用。口服每日5次、剂量为300 - 1000 mg/kg时，可使瘢痕组织的抗张强度显著增加。
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