血管性血友病中血小板对阿司匹林的敏感性
Sensitivity of platelets to aspirin in von Willebrand's disease.
作者信息
Leslie J, Mason D Y
出版信息
J Clin Pathol. 1970 Sep;23(6):526-8. doi: 10.1136/jcp.23.6.526.
Abstract
The sensitivity of collagen-induced platelet aggregation to aspirin was measured in vitro on platelet-rich plasma from 20 normal subjects and five patients with von Willebrand's disease. Although aspirin tolerance tests performed in vivo at the same time showed an abnormal prolongation of the bleeding time in three of the patients studied, no evidence was found for an enhanced sensitivity to aspirin in vitro.
摘要
在体外对20名正常受试者和5名血管性血友病患者的富血小板血浆进行了胶原诱导的血小板聚集对阿司匹林敏感性的检测。尽管同时在体内进行的阿司匹林耐量试验显示，在研究的3名患者中出血时间异常延长，但未发现体外对阿司匹林的敏感性增强的证据。
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