Aldridge W N
Bull World Health Organ. 1971;44(1-3):25-30.
This paper outlines our knowledge of the reaction of organophosphorus compounds and carbamates with esterases, examples of particular aspects of the reaction being confined to cholinesterases, although the general principles discussed apply to all B-esterases. Mathematical expressions are given for the different rate constants, and some of the factors that may affect the response of insect and mammalian cholinesterases to organophosphorus compounds and carbamates are discussed.
本文概述了我们对有机磷化合物和氨基甲酸酯与酯酶反应的认识,尽管所讨论的一般原理适用于所有B酯酶,但反应特定方面的例子仅限于胆碱酯酶。给出了不同速率常数的数学表达式,并讨论了一些可能影响昆虫和哺乳动物胆碱酯酶对有机磷化合物和氨基甲酸酯反应的因素。