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关于尼泊尔鼠疫疫情的临床与流行病学观察

Clinical and epidemiological observations on an outbreak of plague in Nepal.

作者信息

LaForce F M, Acharya I L, Stott G, Brachman P S, Kaufman A F, Clapp R F, Shah N K

出版信息

Bull World Health Organ. 1971;45(6):693-706.

PMID:5317008
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2427975/
Abstract

In the autumn of 1967, plague broke out among hill people in western Nepal, a country that had not previously reported human plague. Two persons were infected from an active sylvatic focus at a grazing area 5 km from Nawra, the village where the epidemic occurred. The second patient introduced plague into the village where the rest of the cases occurred. Clinical and epidemiological evidence suggests that plague was spread both by the airborne route, resulting in 6 cases of tonsillar plague and 1 case of primary pneumonic plague, as well as by infected fleas, resulting in 17 cases of bubonic plague. Since no evidence of a rodent epizootic was uncovered in the village itself, and because of the distinct clustering of the bubonic cases, human-to-human spread of plague by infected ectoparasite vectors, presumably Pulex irritans, is thought to have occurred.This focus probably represents the most southerly boundary of the central Asian plague area yet identified.

摘要

1967年秋,尼泊尔西部山区居民中爆发了鼠疫,该国此前未曾报告过人间鼠疫。在距离疫情发生村庄瑙拉5公里的一个放牧区,有两人从活跃的自然疫源地感染。第二名患者将鼠疫传入了其余病例发生的村庄。临床和流行病学证据表明,鼠疫通过空气传播,导致6例扁桃体鼠疫和1例原发性肺鼠疫,同时也通过感染跳蚤传播,导致17例腺鼠疫。由于在村庄本身未发现啮齿动物 epizootic 的证据,且由于腺鼠疫病例明显聚集,据推测是感染的外寄生媒介(可能是致痒蚤)在人与人之间传播了鼠疫。这个疫源地可能代表了迄今已确定的中亚鼠疫区最南端的边界。

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本文引用的文献

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