Weise W, Quent P
Zentralbl Gynakol. 1979;101(19):1244-9.
Definitions are offered for the concepts of sterility and infertility. The notion of infertility is expanded to cover not only habitual abortions (three or more miscarriages) but, as well, deliveries of defective children. --Five-hundred and fifty-five pregnancies so far have occurred to 240 infertile probands, among them 78 with habitual abortions and 162 with damaged children. Only one in ten of those pregnancies resulted in clinically intact live birth. --Abortion was the result of 95 per cent of all pregnancies of the women with habitual abortion. The same applied to 25 per cent of all pregnancies of the above women with defective children (e.g. Down's syndrome, neural tube defects, diaphragmatic hernia, hydrocephalus, and progressive muscular dystrophy). A damaged child was born in more than 50 per cent of the latter pregnancy cases. --The number of children born by 162 women has been 181, with only 96 of them alive. The causality relationship between abortion and birth of defective children is discussed. --Infertile women should be given special attention, before conception takes place, and they should be kept under intensive care to the end of pregnancy.
文中给出了不育和不孕的概念定义。不孕的概念不仅涵盖习惯性流产（三次或三次以上流产），还包括产出有缺陷婴儿的情况。——到目前为止，240名不孕先证者已怀孕555次，其中78例为习惯性流产，162例产出有缺陷婴儿。这些怀孕中只有十分之一最终产出临床健康的活产婴儿。——习惯性流产女性的所有怀孕中有95%以流产告终。产出有缺陷婴儿（如唐氏综合征、神经管缺陷、膈疝、脑积水和进行性肌营养不良）的上述女性的所有怀孕中，25%也是如此。后一类怀孕案例中有超过50%产出有缺陷婴儿。——162名女性所生子女数量为181名，其中只有96名存活。文中讨论了流产与产出有缺陷婴儿之间的因果关系。——不孕女性在受孕前应给予特别关注，孕期应进行强化护理直至分娩结束。
