Nielsen M, Albrechtsen R, Johnsen N J, Visfeldt J
Acta Otolaryngol. 1979;88(5-6):462-7. doi: 10.3109/00016487909137195.
Two cases are presented of malignant tumour of the parotid gland following sialography with Thorotrast, 28 and 45 years previously. Both cases were histologically established as squamous cell carcinoma and the presence of Thorotrast in the tumours was confirmed by autohistoradiography. It is suggested that the tumours may have developed from metaplastic ductal epithelium after many years of exposure to the alpha radiation from Thorotrast deposits in the gland.
本文报告2例腮腺恶性肿瘤，分别在28年前和45年前接受了含钍造影剂的涎腺造影检查。2例组织学检查均确诊为鳞状细胞癌，通过自动放射自显影证实肿瘤内存在含钍造影剂。提示肿瘤可能是由于多年来暴露于腺体中含钍造影剂沉积物的α射线，导致导管上皮化生后发展而来。
