Peña L, Peña M, Gonzalez J, Claro A
Acta Paediatr Acad Sci Hung. 1979;20(1):99-103.
One hundred four children, six to fourteen years of age, with primary exogenous obesity were randomly distributed in order to be subjected to two different diets, ketogenic (low carbohydrate) and hypocaloric, for eight weeks. Body weight, serum triglycerides, cholesterol, a glucose tolerance test, blood glucose and plasma insulin determination were performed before and after both diets. The results revealed significant differences in body weight and triglyceride concentrations with the two diets although they were more remarkable with the ketogenic diet. There were significant differences in the fasting insulin levels, insulinogenic index, and insulin concentration after a glucose tolerance test in the patients subjected to a ketogenic diet.
104名6至14岁的原发性外源性肥胖儿童被随机分组,接受两种不同饮食,即生酮(低碳水化合物)饮食和低热量饮食,为期8周。在两种饮食前后均进行体重、血清甘油三酯、胆固醇、葡萄糖耐量试验、血糖和血浆胰岛素测定。结果显示,两种饮食在体重和甘油三酯浓度方面存在显著差异,尽管生酮饮食的差异更为显著。接受生酮饮食的患者在空腹胰岛素水平、胰岛素生成指数和葡萄糖耐量试验后的胰岛素浓度方面存在显著差异。