Sargent A U, Myers J, Rose B, Richter M
Immunology. 1966 Mar;10(3):199-210.
The organ and species specificity of rat hepato-cellular antigens has been studied. Lung and heart share a common group of antigens with the kidney and liver, while the kidney contains those antigens in common with the liver which are not present in either lung or heart. Absorption of anti-rat liver serum with rat kidney conferred on it strict specificity for the antigens present within the cytoplasm of the rat hepatic parenchymal cell. The results obtained from the study of the species distribution of the organ specific hepato-cellular antigens suggest that each animal species is characterized by the presence of species specific hepatic antigens, in addition to which there exists a group of antigens which cross species barriers and are present in all species investigated.
已对大鼠肝细胞抗原的器官和物种特异性进行了研究。肺和心脏与肾脏和肝脏共有一组共同抗原，而肾脏含有与肝脏共有的、在肺或心脏中不存在的那些抗原。用大鼠肾脏吸收抗大鼠肝脏血清，使其对大鼠肝实质细胞质内存在的抗原具有严格的特异性。对器官特异性肝细胞抗原的物种分布研究结果表明，每种动物物种除了存在物种特异性肝抗原外，还存在一组跨越物种屏障且在所研究的所有物种中都存在的抗原。
