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用同源或异源肝脏免疫的大鼠中自身抗体的产生。

Production of autoantibodies in rats immunized with homologous or heterologous liver.

作者信息

Richter M, Sargent A U, Myers J, Rose B

出版信息

Immunology. 1966 Mar;10(3):211-5.

Abstract

Immunization of rats with rat liver resulted in the production of antibodies which reacted with autologous liver, as determined by haemagglutination. The antisera were also capable of reacting with heterologous and homologous liver. The specificity of the reaction with autologous liver was confirmed by fluorescence microscopy. Rat anti-rabbit liver antisera showed the same specificity for rat liver when tested with other rat organs. These antisera were also capable of reacting with autologous rat livers.

摘要

用大鼠肝脏对大鼠进行免疫接种后,通过血凝试验测定发现产生了与自体肝脏发生反应的抗体。这些抗血清也能够与异种和同种肝脏发生反应。荧光显微镜检查证实了与自体肝脏反应的特异性。用其他大鼠器官进行检测时,大鼠抗兔肝脏抗血清对大鼠肝脏表现出相同的特异性。这些抗血清也能够与自体大鼠肝脏发生反应。

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The breakdown of immunological tolerance.免疫耐受性的破坏。
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