Nakamura H
J Bacteriol. 1966 Nov;92(5):1447-52. doi: 10.1128/jb.92.5.1447-1452.1966.
Nakamura, Hakobu (Konan University, Kobe, Japan). Acriflavine-binding capacity of Escherichia coli in relation to acriflavine sensitivity and metabolic activity. J. Bacteriol. 92:1447-1452. 1966.-Inheritance of the acriflavine resistance gene by an acriflavine-sensitive strain of Escherichia coli K-12 resulted in a reduction in the cellular accumulation of acriflavine and other basic dyes, but had no effect on the accumulation of acid dyes. In both acriflavine-resistant and -sensitive strains, the cooling of cells from 37 to 0 C increased acriflavine accumulation. This increased accumulation was released from the cells after restoration to 37 C. Acriflavine accumulation was increased by carbon shortage and by metabolic disturbance caused by potassium cyanide, arsenite, puromycin, chloramphenicol, 2-thiouracil, and 8-azaguanine. The functional relation of acrifiavine accumulation to the acriflavine concentration of the medium suggests that adsorption is involved in the accumulation.
中村，叶布（日本神户甲南大学）。大肠杆菌的吖啶黄素结合能力与吖啶黄素敏感性和代谢活性的关系。《细菌学杂志》92:1447 - 1452。1966年。——对吖啶黄素敏感的大肠杆菌K - 12菌株对吖啶黄素抗性基因的遗传导致细胞对吖啶黄素和其他碱性染料的积累减少，但对酸性染料的积累没有影响。在抗吖啶黄素和对吖啶黄素敏感的菌株中，将细胞从37℃冷却至0℃会增加吖啶黄素的积累。恢复到37℃后，这种增加的积累会从细胞中释放出来。碳缺乏以及由氰化钾、亚砷酸盐、嘌呤霉素、氯霉素、2 - 硫尿嘧啶和8 - 氮鸟嘌呤引起的代谢紊乱会增加吖啶黄素的积累。吖啶黄素积累与培养基中吖啶黄素浓度的功能关系表明吸附参与了积累过程。
