青春期对骨骼生长和矿化速率的影响：对男性青春期延迟的观察
Effect of puberty on rates of bone growth and mineralisation: with observations in male delayed puberty.
作者信息
Krabbe S, Christiansen C, Rødbro P, Transbøl I
出版信息
Arch Dis Child. 1979 Dec;54(12):950-3. doi: 10.1136/adc.54.12.950.
Abstract
The bone mineral content (BMC) and body height were measured in 301 normal children and adolescents aged 7--20 years, and in 8 boys with constitutional delayed puberty aged 14--17 years. Serum testosterone was measured in the last group as well as in a subpopulation of the normal children and adolescents. The growth spurt, which coincided with a steep increase of serum testosterone in boys, indicated a great change in skeletal growth and mineralisation in both sexes. After the growth spurt, linear growth slowed down considerably while bone mineralisation rose steeply. When low levels of serum testosterone were maintained, as in delayed puberty, these combined changes of skeletal growth and mineralisation did not occur. It is suggested that gonadal hormones are the true initiators of the short-lived growth spurt as well as of prolonged acceleration of bone mineralisation.
摘要
对301名7至20岁的正常儿童和青少年以及8名14至17岁的体质性青春期延迟男孩进行了骨矿物质含量（BMC）和身高测量。对最后一组以及正常儿童和青少年亚组测量了血清睾酮。生长突增与男孩血清睾酮的急剧增加同时出现，表明男女骨骼生长和矿化都发生了巨大变化。生长突增后，线性生长显著减缓，而骨矿化急剧上升。当血清睾酮维持在低水平时，如青春期延迟，骨骼生长和矿化的这些联合变化不会发生。提示性腺激素是短暂生长突增以及骨矿化长期加速的真正启动因素。
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Effect of puberty on rates of bone growth and mineralisation: with observations in male delayed puberty.青春期对骨骼生长和矿化速率的影响：对男性青春期延迟的观察
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