Villaca L M, de Macedo D D
Arq Neuropsiquiatr. 1979 Dec;37(4):435-42. doi: 10.1590/s0004-282x1979000400010.
Subacute progressive panencephalitis is usually a progressive and fatal disease, being uncommon temporary or definitive remissions. A three years old boy, previously vaccinated against measles, developed trembling, progressive and severe mental deterioration, partial seizures and myoclonic jerks. The electroencephalogram showed periodic high amplitude waves concomitantly with myoclonic jerks and the cerebrospinal fluid revealed an increase of the gammaglobulin fraction (16,8), benjoin coloidal reaction shifted to the left and the antimeasles antibody titres were positive (complement fixation text 1:16; neutralization test 1:32). In spite of that, two months after the beginning of the illness the patient showed mental and motor improvement and similar modifications of the electroencephalographic aspects and now, eleven months later, is well, remaining only a slight motor and mental deficiency.
亚急性进行性全脑炎通常是一种进行性致命疾病,很少有暂时或确定的缓解。一名3岁男孩,之前接种过麻疹疫苗,出现颤抖、进行性严重精神衰退、部分癫痫发作和肌阵挛性抽搐。脑电图显示与肌阵挛性抽搐同时出现周期性高幅波,脑脊液显示γ球蛋白分数增加(16,8),本琼胶体反应左移,抗麻疹抗体滴度呈阳性(补体结合试验1:16;中和试验1:32)。尽管如此,疾病开始两个月后患者出现精神和运动改善,脑电图表现也有类似变化,现在,11个月后,患者情况良好,仅残留轻微的运动和精神缺陷。