Horwitz M A, Marr J S, Merson M H, Dowell V R, Ellis J M
Lancet. 1975 Nov 1;2(7940):861-3. doi: 10.1016/s0140-6736(75)90246-9.
In December, 1974, three cases of botulism occurred in a family; two were fatal. The first patient died after a 10-day illness without botulism being suspected. 4 days later, after a 2-day illness, the second patient was diagnosed as having botulism after a cardiorespiratory arrest; she died 3 days later. In the third patient, the only symptom was dysphagia. Clostridium botulinum type B was found in stool specimens from all three patients. Home-canned (bottled) mushrooms, which were found to contain C. botulinum type B and its toxin, were believed to be responsible for the outbreak; mushrooms were found at necropsy in the gastrointestinal tracts of both patients who died. Heat treatment of the mushrooms during canning had been inadequate.
1974年12月，一个家庭中发生了3例肉毒中毒病例；其中2例死亡。首例患者在患病10天后死亡，当时未怀疑是肉毒中毒。4天后，第二例患者在患病2天后因心肺骤停被诊断为肉毒中毒；3天后死亡。第三例患者唯一的症状是吞咽困难。在所有3例患者的粪便标本中均发现了B型肉毒梭菌。据信，家庭自制罐装（瓶装）蘑菇是此次疫情的罪魁祸首，这些蘑菇被发现含有B型肉毒梭菌及其毒素；在两名死亡患者的尸检中，在胃肠道中发现了蘑菇。罐装过程中蘑菇的热处理不充分。
