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Protective role of S-adenosyl-l-methionine against acetaminophen induced mortality and hepatotoxicity in mice.

作者信息

Stramentinoli G, Pezzoli C, Galli-Kienle M

出版信息

Biochem Pharmacol. 1979 Dec 15;28(24):3567-71. doi: 10.1016/0006-2952(79)90401-5.

DOI:10.1016/0006-2952(79)90401-5
PMID:533559
Abstract
摘要

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Protective role of S-adenosyl-l-methionine against acetaminophen induced mortality and hepatotoxicity in mice.S-腺苷-L-甲硫氨酸对乙酰氨基酚诱导的小鼠死亡和肝毒性的保护作用。
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Studies on the effects of L-ascorbic acid on acetaminophen-induced hepatotoxicity. II. An in vivo assessment in mice of the protection afforded by various dosage forms of ascorbate.L-抗坏血酸对乙酰氨基酚诱导的肝毒性影响的研究。II. 小鼠体内不同剂型抗坏血酸盐保护作用的评估
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Temporal study of acetaminophen (APAP) and S-adenosyl-L-methionine (SAMe) effects on subcellular hepatic SAMe levels and methionine adenosyltransferase (MAT) expression and activity.对乙酰氨基酚（APAP）和 S-腺苷-L-蛋氨酸（SAMe）对肝亚细胞 SAMe 水平和蛋氨酸腺苷转移酶（MAT）表达和活性的时间研究。
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Protective role of S-adenosyl-L-methionine on liver injury induced by D-galactosamine in rats.
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Effect of different doses of S-adenosyl-L-methionine on paracetamol hepatotoxicity in a mouse model.
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