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Clofibrate-induced increase in carnitine and acylcarnitine content in rats.

作者信息

Kähönen M T

出版信息

Biochem Pharmacol. 1979 Dec 15;28(24):3674-7. doi: 10.1016/0006-2952(79)90418-0.

DOI:10.1016/0006-2952(79)90418-0
PMID:533567
Abstract
摘要

相似文献

1
Clofibrate-induced increase in carnitine and acylcarnitine content in rats.氯贝丁酯诱导大鼠体内肉碱和酰基肉碱含量增加。
Biochem Pharmacol. 1979 Dec 15;28(24):3674-7. doi: 10.1016/0006-2952(79)90418-0.
2
Interaction of carnitine and propionate with pyruvate oxidation by hepatocytes from clofibrate-treated rats: importance of coenzyme A availability.肉碱和丙酸盐与氯贝丁酯处理大鼠肝细胞丙酮酸氧化的相互作用:辅酶A可用性的重要性。
J Nutr. 1992 Feb;122(2):234-40. doi: 10.1093/jn/122.2.234.
3
Effects of ciprofibrate and 2-[5-(4-chlorophenyl)pentyl]oxirane-2-carboxylate (POCA) on the distribution of carnitine and CoA and their acyl-esters and on enzyme activities in rats. Relation between hepatic carnitine concentration and carnitine acetyltransferase activity.环丙贝特和2-[5-(4-氯苯基)戊基]环氧乙烷-2-羧酸盐(POCA)对大鼠体内肉碱和辅酶A及其酰基酯分布以及酶活性的影响。肝脏肉碱浓度与肉碱乙酰转移酶活性之间的关系。
Biochem J. 1988 Jul 15;253(2):337-43. doi: 10.1042/bj2530337.
4
Clofibrate enhancement of mitochondrial carnitine transport system of rat liver and augmentation of liver carnitine and gamma-butyrobetaine hydroxylase activity by thyroxine.氯贝丁酯对大鼠肝脏线粒体肉碱转运系统的增强作用以及甲状腺素对肝脏肉碱和γ-丁基甜菜碱羟化酶活性的增强作用。
Biochim Biophys Acta. 1980 Mar 21;617(3):363-70. doi: 10.1016/0005-2760(80)90002-8.
5
Induction of carnitine acetyltransferase by clofibrate in rat liver.氯贝丁酯对大鼠肝脏中肉碱乙酰转移酶的诱导作用。
Biochem J. 1981 Jan 15;194(1):249-55. doi: 10.1042/bj1940249.
6
Mechanism of increased hepatic concentration of carnitine by clofibrate.
Am J Physiol. 1986 Sep;251(3 Pt 1):E311-5. doi: 10.1152/ajpendo.1986.251.3.E311.
7
Hepatic release of carnitine: effect of increased concentration by clofibrate treatment.
Biochem Med Metab Biol. 1992 Feb;47(1):21-30. doi: 10.1016/0885-4505(92)90004-i.
8
Paradoxical effects of clofibrate on liver and muscle metabolism in rats. Induction of myotonia and alteration of fatty acid and glucose oxidation.氯贝丁酯对大鼠肝脏和肌肉代谢的反常效应。肌强直的诱导以及脂肪酸和葡萄糖氧化的改变。
J Clin Invest. 1979 Aug;64(2):405-12. doi: 10.1172/JCI109476.
9
Treatment with pharmacological peroxisome proliferator-activated receptor alpha agonist clofibrate causes upregulation of organic cation transporter 2 in liver and small intestine of rats.用药理剂量的过氧化物酶体增殖物激活受体α激动剂氯贝丁酯治疗可导致大鼠肝脏和小肠中有机阳离子转运体2的上调。
Pharmacol Res. 2007 Aug;56(2):175-83. doi: 10.1016/j.phrs.2007.06.001. Epub 2007 Jun 16.
10
Stimulation of catalase synthesis and increase of carnitine acetyltransferase activity in the liver of intact female rats fed clofibrate.氯贝丁酯喂养的未交配雌性大鼠肝脏中过氧化氢酶合成的刺激及肉碱乙酰转移酶活性的增加。
J Biochem. 1979 Mar;85(3):847-56.