大肠杆菌中芳香族生物合成第一步反应所涉及的同工酶的遗传与生化分析。
Genetic and biochemical analysis of the isoenzymes concerned in the first reaction of aromatic biosynthesis in Escherichia coli.
作者信息
Wallace B J, Pittard J
出版信息
J Bacteriol. 1967 Jan;93(1):237-44. doi: 10.1128/jb.93.1.237-244.1967.
Abstract
Mutant strains of Escherichia coli K-12 were isolated possessing mutations which affected the tyrosine-inhibitable 3-deoxy-d-arabinoheptulosonic acid-7-phosphate (DAHP) synthetase, the phenylalanine-inhibitable DAHP synthetase, or the tryptophan-repressible DAHP synthetase. The mutations causing the loss of each of these activities have been mapped and are widely separated from each other on the E. coli chromosome. Chromatography on diethylaminoethyl cellulose columns allowed the recognition of four peaks of activity.
摘要
分离出了大肠杆菌K-12的突变菌株，这些菌株具有影响酪氨酸可抑制的3-脱氧-D-阿拉伯庚酮糖酸-7-磷酸（DAHP）合成酶、苯丙氨酸可抑制的DAHP合成酶或色氨酸可阻遏的DAHP合成酶的突变。导致这些活性丧失的突变已被定位，并且在大肠杆菌染色体上彼此相距很远。在二乙氨基乙基纤维素柱上进行色谱分析可识别出四个活性峰。
相似文献
1
Genetic and biochemical analysis of the isoenzymes concerned in the first reaction of aromatic biosynthesis in Escherichia coli.
J Bacteriol. 1967 Jan;93(1):237-44. doi: 10.1128/jb.93.1.237-244.1967.
2
Repression of aromatic amino acid biosynthesis in Escherichia coli K-12.
J Bacteriol. 1971 Oct;108(1):386-99. doi: 10.1128/jb.108.1.386-399.1971.
3
Repression of 3-deoxy-D-arabinoheptulosonic acid-7-phosphate synthetase (trp) and enzymes of the tryptophan pathway in Escherichia coli K-12.
J Bacteriol. 1971 Aug;107(2):406-14. doi: 10.1128/jb.107.2.406-414.1971.
4
Chromatography of 3-deoxy-D-arabinoheptulosonic acid-7-phosphate synthetase (trp) on diethylaminoethyl cellulose: a correction.
J Bacteriol. 1967 Oct;94(4):1279-80. doi: 10.1128/jb.94.4.1279-1280.1967.
5
Inhibition of 3-deoxy-d-arabinoheptulosonic acid-7-phosphate synthetase (trp) in Escherichia coli.
J Bacteriol. 1969 Mar;97(3):1242-7. doi: 10.1128/jb.97.3.1242-1247.1969.
6
Regulation of aromatic amino acid biosynthesis in Escherichia coli K-12: control of the aroF-tyrA operon in the absence of repression control.
J Bacteriol. 1980 Aug;143(2):613-20. doi: 10.1128/jb.143.2.613-620.1980.
7
Phenylalanine and tyrosine biosynthesis in Escherichia coli K-12: mutants derepressed for 3-deoxy-D-arabinoheptulosonic acid 7-phosphate synthetase (phe), 3-deoxy-D-arabinoheptulosonic acid 7-phosphate synthetase (tyr), chorismate mutase T-prephenate dehydrogenase, and transaminase A.
J Bacteriol. 1971 Oct;108(1):400-9. doi: 10.1128/jb.108.1.400-409.1971.
8
Regulator gene controlling enzymes concerned in tyrosine biosynthesis in Escherichia coli.
J Bacteriol. 1969 Mar;97(3):1234-41. doi: 10.1128/jb.97.3.1234-1241.1969.
9
3-Deoxy-D-arabino-heptulosonic acid 7-phosphate synthase mutants of Salmonella typhimurium.
J Bacteriol. 1975 Dec;124(3):1312-20. doi: 10.1128/jb.124.3.1312-1320.1975.
10
Tryptophan- and indole-excreting prototrophic mutant of Escherichia coli.
J Bacteriol. 1964 May;87(5):1051-5. doi: 10.1128/jb.87.5.1051-1055.1964.
引用本文的文献
1
Quaternary structure is an essential component that contributes to the sophisticated allosteric regulation mechanism in a key enzyme from Mycobacterium tuberculosis.
PLoS One. 2017 Jun 30;12(6):e0180052. doi: 10.1371/journal.pone.0180052. eCollection 2017.
2
Neisseria meningitidis expresses a single 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase that is inhibited primarily by phenylalanine.
Protein Sci. 2013 Aug;22(8):1087-99. doi: 10.1002/pro.2293. Epub 2013 Jun 27.
3
The genome of Geobacter bemidjiensis, exemplar for the subsurface clade of Geobacter species that predominate in Fe(III)-reducing subsurface environments.
BMC Genomics. 2010 Sep 9;11:490. doi: 10.1186/1471-2164-11-490.
4
Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis.
J Biol Chem. 2010 Oct 1;285(40):30567-76. doi: 10.1074/jbc.M110.111856. Epub 2010 Jul 27.
5
Insight into siderophore-carrying peptide biosynthesis: enterobactin is a precursor for microcin E492 posttranslational modification.
Antimicrob Agents Chemother. 2007 Oct;51(10):3546-53. doi: 10.1128/AAC.00261-07. Epub 2007 Jul 23.
6
Microbial origin of plant-type 2-keto-3-deoxy-D-arabino-heptulosonate 7-phosphate synthases, exemplified by the chorismate- and tryptophan-regulated enzyme from Xanthomonas campestris.
J Bacteriol. 2001 Jul;183(13):4061-70. doi: 10.1128/JB.183.13.4061-4070.2001.
7
Regulation of aromatic amino acid biosynthesis in Escherichia coli K-12: control of the aroF-tyrA operon in the absence of repression control.
J Bacteriol. 1980 Aug;143(2):613-20. doi: 10.1128/jb.143.2.613-620.1980.
8
Control of cell septation by lateral wall extension in a pH-conditional morphology mutant of Klebsiella pneumoniae.
J Bacteriol. 1980 Apr;142(1):43-51. doi: 10.1128/jb.142.1.43-51.1980.
9
Regulatory isozymes of 3-deoxy-D-arabinoheptulosonate 7-phosphate synthase in the cyanobacterium Anabaena sp. strain ATCC 29151.
J Bacteriol. 1981 Oct;148(1):361-4. doi: 10.1128/jb.148.1.361-364.1981.
10
Regulation of chemoautotrophic metabolism. 3. DAHP synthetase in Thiobacillus neapolitanus.
Arch Mikrobiol. 1969;69(4):360-9. doi: 10.1007/BF00408576.
本文引用的文献
1
Transduction in Escherichia Coli K-12.
Genetics. 1956 Jan;41(1):142-56. doi: 10.1093/genetics/41.1.142.
2
Protein measurement with the Folin phenol reagent.
J Biol Chem. 1951 Nov;193(1):265-75.
3
Hyper-production of beta-galactosidase by Escherichia coli bacteria.
Cold Spring Harb Symp Quant Biol. 1961;26:239-45. doi: 10.1101/sqb.1961.026.01.029.
4
PARALLEL MODIFICATIONS CAUSED BY MUTATIONS IN TWO ENZYMES CONCERNED WITH THE BIOSYNTHESIS OF THREONINE IN ESCHERICHIA COLI.
Biochem Biophys Res Commun. 1965 May 3;19:546-50. doi: 10.1016/0006-291x(65)90160-9.
5
FALSE FEEDBACK INHIBITION OF AROMATIC AMINO ACID BIOSYNTHESIS BY BETA-2-THIENYLALANINE.
Biochim Biophys Acta. 1965 Jan 11;95:54-62. doi: 10.1016/0005-2787(65)90210-8.
6
END-PRODUCT REGULATION OF THE GENERAL AROMATIC-PATHWAY IN ESCHERICHIA COLI W.
Biochim Biophys Acta. 1963 Sep 3;77:170-2. doi: 10.1016/0006-3002(63)90489-x.
7
The control of 3-deoxy-D-arabino-heptulosonic acid 7-phosphate synthesis by phenylalanine and tyrosine.
J Biol Chem. 1962 Nov;237:3566-70.
8
Genetic variation in the sex factor of Escherichia coli.
J Bacteriol. 1960 Mar;79(3):321-30. doi: 10.1128/jb.79.3.321-330.1960.
9
2-Keto-3-deoxy-D-arabo-heptonic acid 7-phosphate synthetase.
J Biol Chem. 1959 Apr;234(4):716-22.
10
Modification of the penicillin technique for the selection of auxotrophic bacteria.
J Bacteriol. 1953 Mar;65(3):348-53. doi: 10.1128/jb.65.3.348-353.1953.
Zotero 插件