Prioreschi P
Can Med Assoc J. 1967 Apr 29;96(17):1221-3.
In recent years evidence has been brought forward supporting the hypothesis that myocardial infarction is not due to thrombotic occlusion of a coronary artery but to a metabolic derangement in a myocardium "conditioned" by coronary atherosclerosis. The author briefly reviews metabolic necroses experimentally induced in the animal and discusses the action of potassium in preventing their development. The basis for the clinical use of potassium and magnesium salts for the prevention of myocardial infarction is also discussed.
近年来,已有证据支持这样一种假说,即心肌梗死并非由冠状动脉血栓性闭塞所致,而是由冠状动脉粥样硬化“预处理”的心肌代谢紊乱引起的。作者简要回顾了在动物身上实验诱导的代谢性坏死,并讨论了钾在预防其发生方面的作用。还讨论了钾盐和镁盐在预防心肌梗死临床应用的依据。