脑啡肽在大肠恶性肿瘤和急性阑尾炎中的情况。
Enkephalins in large bowel malignancy and in acute appendicitis.
作者信息
Davis W G, Tormey W P, Delaney P V
出版信息
Gut. 1979 Oct;20(10):865-7. doi: 10.1136/gut.20.10.865.
Abstract
Leucine and methionine enkephalins were measured by biological assay in normal colon, adenocarcinoma of the colon, carcinoma of the caecum, and in normal and inflamed appendix. Methionine enkephalin levels in both the adenocarcinomas and inflamed appendices were significantly higher than in normal controls. No significant change occurred in leucine enkephalin levels. The caecal tumours were anaplastic and contained no demonstrable opioid activity.
摘要
通过生物测定法检测了正常结肠、结肠腺癌、盲肠癌以及正常和发炎阑尾中亮氨酸脑啡肽和甲硫氨酸脑啡肽的含量。腺癌和发炎阑尾中甲硫氨酸脑啡肽的水平均显著高于正常对照组。亮氨酸脑啡肽水平未发生显著变化。盲肠肿瘤为间变性，未检测到明显的阿片样物质活性。
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