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溴隐亭对速尿引起的血浆醛固酮反应的抑制作用。

Inhibition of the plasma-aldosterone response to frusemide by bromocriptine.

作者信息

Edwards C R, Miall P A, Hanker J P, Thorner M O, Al-Dujaili E A, Besser G M

出版信息

Lancet. 1975 Nov 8;2(7941):903-5. doi: 10.1016/s0140-6736(75)92132-7.

DOI:10.1016/s0140-6736(75)92132-7
PMID:53377
Abstract

The administration of the long-acting dopaminergic agonist bromocriptine to five healthy volunteers inhibited the rise in plasma-aldosterone that normally follows the administration of frusemide. This inhibition was not due to a lowering of plasma-renin activity. It is suggested that dopamine may modulate the normal secretion of aldosterone either directly, or indirectly, possible by inhibition of prolactin secretion.

摘要

给五名健康志愿者服用长效多巴胺能激动剂溴隐亭,可抑制通常在服用速尿后出现的血浆醛固酮升高。这种抑制作用并非由于血浆肾素活性降低所致。有人提出,多巴胺可能直接或间接地调节醛固酮的正常分泌,可能是通过抑制催乳素分泌来实现的。

相似文献

1
Inhibition of the plasma-aldosterone response to frusemide by bromocriptine.溴隐亭对速尿引起的血浆醛固酮反应的抑制作用。
Lancet. 1975 Nov 8;2(7941):903-5. doi: 10.1016/s0140-6736(75)92132-7.
2
Lack of effect of prolactin inhibition by alpha-bromoergocriptine (CB 154) on plasma aldosterone in anephric and non-nephrectomized patients on regular haemodialysis.α-溴麦角环肽(CB 154)抑制催乳素对无肾和未行肾切除的规律血液透析患者血浆醛固酮水平无影响。
Acta Endocrinol (Copenh). 1977 Jul;85(3):587-94. doi: 10.1530/acta.0.0850587.
3
Effects of metoclopramide and bromocriptine on the renin-angiotensin-aldosterone system in man. Dopaminergic control of aldosterone.甲氧氯普胺和溴隐亭对人体肾素-血管紧张素-醛固酮系统的作用。醛固酮的多巴胺能调控。
J Clin Invest. 1979 Apr;63(4):727-35. doi: 10.1172/JCI109356.
4
Dopaminergic effects on kidney function and responsiveness of aldosterone, plasma renin activity, prolactin, catecholamines, and blood pressure to stimulation in patients with prolactinoma. Comparison of the efficacy of pergolide and bromocriptine therapy.多巴胺能对泌乳素瘤患者肾功能以及醛固酮、血浆肾素活性、泌乳素、儿茶酚胺和血压对刺激的反应性的影响。培高利特与溴隐亭治疗效果的比较。
Arzneimittelforschung. 1988 Feb;38(2):296-300.
5
Aldosterone suppression with dopamine infusion in low-renin hypertension.低肾素性高血压患者中多巴胺输注对醛固酮的抑制作用
J Clin Invest. 1983 Sep;72(3):754-66. doi: 10.1172/JCI111046.
6
Bromocriptine does not inhibit the aldosterone response to sodium depletion.
J Clin Endocrinol Metab. 1982 Jul;55(1):162-5. doi: 10.1210/jcem-55-1-162.
7
Dopaminergic inhibition of metoclopramide-induced aldosterone secretion in man. Dissociation of responses to dopamine and bromocriptine.甲氧氯普胺诱导的人体醛固酮分泌的多巴胺能抑制作用。对多巴胺和溴隐亭反应的解离。
J Clin Invest. 1980 Jul;66(1):10-8. doi: 10.1172/JCI109822.
8
Renin and aldosterone in hypothyroidism: relation to excretion of sodium and potassium.
Clin Endocrinol (Oxf). 1980 May;12(5):483-9. doi: 10.1111/j.1365-2265.1980.tb02739.x.
9
Hyperprolactinaemia and antihypertensive effect of bromocriptine in essential hypertension. Identification of abnormal central dopamine control.溴隐亭对原发性高血压患者的高泌乳素血症及降压作用。中枢多巴胺控制异常的鉴定。
Lancet. 1977 Jul 30;2(8031):211-4. doi: 10.1016/s0140-6736(77)92832-x.
10
Bromocriptine: lack of effect on the angiotensin II and aldosterone responses to sodium deprivation.溴隐亭:对血管紧张素II及醛固酮对钠缺乏的反应无影响。
Clin Endocrinol (Oxf). 1978 Aug;9(2):155-61. doi: 10.1111/j.1365-2265.1978.tb02193.x.

引用本文的文献

1
An investigation of the importance of the adrenal gland to the action of dopamine in the rat kidney.肾上腺对多巴胺在大鼠肾脏中作用的重要性研究。
Br J Pharmacol. 1983 May;79(1):103-8. doi: 10.1111/j.1476-5381.1983.tb10501.x.
2
Primary tissue culture of human adrenocortical Conn's adenomata. Bromocriptine as a possible agonist-antagonist of angiotensin at the cellular level.人肾上腺皮质Conn腺瘤的原代组织培养。溴隐亭作为血管紧张素在细胞水平上可能的激动剂-拮抗剂。
Cell Tissue Res. 1984;236(1):67-72. doi: 10.1007/BF00216514.
3
The endocrine profile of bromocriptine: its application in endocrine diseases.
溴隐亭的内分泌概况:其在内分泌疾病中的应用。
J Neural Transm. 1981;51(1-2):61-82. doi: 10.1007/BF01664005.
4
Inhibitory effect of somatostatin on the aldosterone response to angiotensin II: in vitro studies.生长抑素对醛固酮对血管紧张素II反应的抑制作用:体外研究
J Endocrinol Invest. 1982 May-Jun;5(3):173-7. doi: 10.1007/BF03349475.
5
Role of dopamine in the regulation of aldosterone and 18-hydroxycorticosterone secretion in man.多巴胺在人体醛固酮和18-羟皮质酮分泌调节中的作用。
J Endocrinol Invest. 1984 Oct;7(5):473-9. doi: 10.1007/BF03348453.
6
Effects of the dopaminergic agonist cianergoline on blood pressure, the renin-angiotensin-aldosterone axis and the sympathetic nervous system in patients with essential hypertension.多巴胺能激动剂西阿尼戈林对原发性高血压患者血压、肾素-血管紧张素-醛固酮轴及交感神经系统的影响
Eur J Clin Pharmacol. 1985;29(1):25-31. doi: 10.1007/BF00547364.
7
Lack of prolactin involvement in corticosteroid secretion.催乳素未参与皮质类固醇分泌。
J Endocrinol Invest. 1987 Feb;10(1):15-20. doi: 10.1007/BF03347142.
8
Stimulation of aldosterone secretion by metoclopramide is not affected by chronic converting enzyme inhibition.
Eur J Clin Pharmacol. 1985;29(2):207-10. doi: 10.1007/BF00547423.
9
Dopamine inhibits angiotensin-stimulated aldosterone biosynthesis in bovine adrenal cells.多巴胺抑制牛肾上腺细胞中血管紧张素刺激的醛固酮生物合成。
J Clin Invest. 1979 Jul;64(1):287-91. doi: 10.1172/JCI109450.
10
Effects of metoclopramide and bromocriptine on the renin-angiotensin-aldosterone system in man. Dopaminergic control of aldosterone.甲氧氯普胺和溴隐亭对人体肾素-血管紧张素-醛固酮系统的作用。醛固酮的多巴胺能调控。
J Clin Invest. 1979 Apr;63(4):727-35. doi: 10.1172/JCI109356.