Thomas B A
Lancet. 1975 Nov 8;2(7941):914-5. doi: 10.1016/s0140-6736(75)92141-8.
A preliminary survey has been carried out to test the feasibility of screening a high-risk group of women for breast cancer, using clinical examination and low-dose mammography, before the establishment of a two-tier screening system of basic well-woman clinics for the over-25s, and breast screening clinics for those over-35s considered to have a higher than average expectation of developing the disease. 7 breast cancers and 1 case of Hodgkin's disease were detected in 618 women (breast cancers 11-3/1000, malignancies 12-9/1000). Though numbers are small they suggest that the women themselves do not suspect the presence of those breast cancers which carry the best prognosis, though being aware of the larger cancers and of many of those benign localised breast lesions requiring surgical treatment.
在为25岁以上女性建立基层健康检查诊所和为35岁以上被认为患乳腺癌风险高于平均水平的女性建立乳腺筛查诊所的两级筛查系统之前，已经进行了一项初步调查，以测试使用临床检查和低剂量乳房X光检查对高危女性群体进行乳腺癌筛查的可行性。在618名女性中检测出7例乳腺癌和1例霍奇金病（乳腺癌发病率为11 - 3/1000，恶性肿瘤发病率为12 - 9/1000）。尽管数量较少，但这表明女性自身并未怀疑那些预后最佳的乳腺癌的存在，不过她们知晓较大的癌症以及许多需要手术治疗的良性局限性乳腺病变。
