Potter J L, Hillman J V
JACEP. 1979 Jan;8(1):26-7. doi: 10.1016/s0361-1124(79)80446-3.
Intense cyanosis in a previously well, 30-month-old, white girl was found to be due to the ingestion of benzocaine. A wide variety of chemical compounds present in many proprietary products, when ingested, can cause this presentation in individuals with structurally normal hemoglobin and normal activity of methemoglobin reductase. The phenomenon appears to be dose-related. Immediate recognition and initiation of appropriate therapy will effect a rapid reversal of the methemoglobinemia, and in some cases, may be life-saving. Caution should be exercised in the use of benzocaine-containing preparations.
一名此前健康的30个月大白人女孩出现严重发绀，经检查发现是由于摄入了苯佐卡因。许多专利产品中含有的多种化合物，被摄入后，可在血红蛋白结构正常且高铁血红蛋白还原酶活性正常的个体中引发这种症状。这种现象似乎与剂量相关。立即识别并开始适当治疗将使高铁血红蛋白血症迅速逆转，在某些情况下，可能会挽救生命。使用含苯佐卡因的制剂时应谨慎。
