Feigelson J, Pécau Y, Bereziat G, Pépin D, Sauvegrain J, Pennaforte F, Roynette A
Nouv Presse Med. 1979 Oct 8;8(38):3029-31.
Biliary lithiasis was discovered in a girl aged 11 suffering from Cystic Fibrosis and who underwent partial small bowel resection for meconium ileus. A cholecystectomy was performed at 15. Examination of the stones showed that they were composed of cholesterol and chemical examination of the bile showed an increase of phospholipids and a decrease in bile salts. There was also a modification of the ratio (Formula: see text) in the serum and the bile. All those factors contribute to the insolubility of cholesterol and to the formation of lithiasis. For all those reasons, the authors recommend a regular radiologic surveillance of the gallbladder in Cystic Fibrosis.
在一名11岁患囊性纤维化且因胎粪性肠梗阻接受部分小肠切除术的女孩中发现了胆石症。该女孩15岁时接受了胆囊切除术。对结石的检查表明它们由胆固醇组成，胆汁的化学检查显示磷脂增加而胆盐减少。血清和胆汁中的比例（公式：见原文）也有改变。所有这些因素都导致胆固醇不溶性增加和结石形成。基于所有这些原因，作者建议对囊性纤维化患者的胆囊进行定期放射学监测。
