Ali M, Fayemi A O, Braun E V, Remy R
Am J Surg Pathol. 1979 Dec;3(6):501-5. doi: 10.1097/00000478-197912000-00003.
Two cases of fibromatosis of the female mammary gland treated by local excision and with a follow-up of 11 and 3 years, respectively, are described. Fibromatosis confined to the breast and not involving the underlying fibroaponeurotic fascia is a rare lesion. Among the handful of cases reported in the literature, diagnostic errors are known to have led to unnecessary mastectomy. In the breast, fibromatosis behaves in the same fashion as in the soft tissues: an aggressive infiltrative lesion with a proclivity for local recurrence following inadequate excision but without potential for distant metastasis. Clinically, it may simulate carcinoma; when suspected histologically during frozen section study, surgical resection should be limited to wide local excision and a definitive plan of therapy deferred until the lesion can be examined carefully with permanent sections.
本文描述了两例女性乳腺纤维瘤病患者,分别接受了局部切除治疗,随访时间分别为11年和3年。局限于乳腺且未累及深面纤维腱膜的纤维瘤病是一种罕见病变。在文献报道的少数病例中,已知诊断错误导致了不必要的乳房切除术。在乳腺中,纤维瘤病的表现与软组织中相同:是一种侵袭性浸润性病变,切除不充分时易局部复发,但无远处转移潜能。临床上,它可能类似癌;在冰冻切片检查时若组织学怀疑为此病,手术切除应限于广泛局部切除,明确的治疗方案应推迟至病变能用永久切片仔细检查时再制定。