Schwarz Graham S, Drotman Michelle, Rosenblatt Ruth, Milner Lawrence, Shamonki Jaime, Osborne Michael P
Department of Surgery, The Breast Center, New York-Presbyterian Hospital, Weill Cornell Medical Center, New York, New York 10021, USA.
Breast J. 2006 Jan-Feb;12(1):66-71. doi: 10.1111/j.1075-122X.2006.00187.x.
Fibromatosis is an uncommon breast lesion that can mimic breast carcinoma in its clinical presentation. We present a case in which excisional biopsy was necessary to establish a diagnosis of fibromatosis. Clinical, diagnostic imaging, and pathologic features are discussed. Magnetic resonance imaging (MRI) has emerged as a tool for further characterization of breast lesions and as a screening modality in high-risk patient populations. Ours marks the second case in which dynamic MRI has been correlated with histologically confirmed primary mammary fibromatosis. Unlike the previous report, MRI in this case mimics breast carcinoma in its morphologic and pharmacokinetic features of enhancement. Wide local excision with clear margins remains the treatment of choice. Current data on radiotherapy and pharmacologic therapy for mammary fibromatosis are reviewed.
纤维瘤病是一种不常见的乳腺病变，其临床表现可酷似乳腺癌。我们报告一例需要切除活检以确诊纤维瘤病的病例。文中讨论了其临床、诊断性影像学及病理学特征。磁共振成像（MRI）已成为进一步明确乳腺病变特征的工具以及高危患者群体的筛查方式。我们的病例是第二例动态MRI与经组织学证实的原发性乳腺纤维瘤病相关的病例。与之前的报告不同，该病例的MRI在强化的形态学和药代动力学特征方面酷似乳腺癌。切缘阴性的广泛局部切除仍是首选治疗方法。本文综述了目前关于乳腺纤维瘤病放疗和药物治疗的数据。
