佛波醇12-肉豆蔻酸酯13-乙酸酯与皮质醇相互作用对大鼠类固醇结合能力的影响。
Effects of phorbol 12-myristate 13-acetate and cortisol interaction on steroid-binding capacity in the rat.
作者信息
Janssens J P, de Loecker W
出版信息
Biochem J. 1979 Nov 15;184(2):361-5. doi: 10.1042/bj1840361.
Abstract
The specificity of the cortisol-receptor protein is examined in plasma and liver cytosol of rats. Phorbol 12-myristate 13-acetate does not inhibit the binding of cortisol to transcortin, nor does it affect the binding capacity of dexamethasone to the intracellular glucocorticoid receptor, but, by interacting with the cortisol molecule, it interferes with hormone-mediated processes in the cell.
摘要
在大鼠的血浆和肝细胞溶胶中检测了皮质醇受体蛋白的特异性。佛波酯不抑制皮质醇与皮质素转运蛋白的结合，也不影响地塞米松与细胞内糖皮质激素受体的结合能力，但通过与皮质醇分子相互作用，它会干扰细胞内激素介导的过程。
相似文献
1
Effects of phorbol 12-myristate 13-acetate and cortisol interaction on steroid-binding capacity in the rat.佛波醇12-肉豆蔻酸酯13-乙酸酯与皮质醇相互作用对大鼠类固醇结合能力的影响。
Biochem J. 1979 Nov 15;184(2):361-5. doi: 10.1042/bj1840361.
2
Concanavalin A-induced glucocorticoid resistance in rat thymus cells: decreased cytoplasmic and nuclear receptor binding of dexamethasone.
J Steroid Biochem. 1976 Nov-Dec;7(11-12):1141-5. doi: 10.1016/0022-4731(76)90046-7.
3
The interaction between different phorbol derivatives and cortisol.
Anticancer Res. 1984 Jul-Oct;4(4-5):263-7.
4
Effects of phorbol ester tumor promoters and hyperplasiogenic agents on cytoplasmic glucocorticoid receptors in epidermis.佛波酯肿瘤启动子和增生剂对表皮细胞质糖皮质激素受体的影响。
J Invest Dermatol. 1982 Dec;79(6):378-82. doi: 10.1111/1523-1747.ep12529883.
5
The structure and regulatory function(s) of cortisol receptor--1: Extragenosomic effects dependent on the cortisol receptor activation.皮质醇受体的结构与调节功能——1：依赖于皮质醇受体激活的非基因组效应。
J Steroid Biochem. 1979 Jul;11(1B):389-400. doi: 10.1016/0022-4731(79)90057-8.
6
Cortisol 17 beta acid, transcortin, and the heterogeneity of rat brain glucocorticoid receptors.皮质醇17β酸、皮质素转运蛋白与大鼠脑糖皮质激素受体的异质性
J Steroid Biochem. 1986 Aug;25(2):285-8. doi: 10.1016/0022-4731(86)90430-9.
7
Effects of D- and L-thyroxine on the glucocorticoid binding capacity of adult rat liver.D-和L-甲状腺素对成年大鼠肝脏糖皮质激素结合能力的影响。
Biochem Biophys Res Commun. 1985 Jun 14;129(2):447-52. doi: 10.1016/0006-291x(85)90171-8.
8
Investigation of the causes of the decrease in enzyme induction after prolonged administration of a hormone: reception of cortisol in rat liver cells.长期给予激素后酶诱导作用降低的原因研究：大鼠肝细胞中皮质醇的摄取
Neurosci Behav Physiol. 1982 Sep-Oct;12(5):380-5. doi: 10.1007/BF01189299.
9
Glucocorticoid binding proteins of human brain cytosol.
Brain Res. 1979 Dec 21;179(1):181-5. doi: 10.1016/0006-8993(79)90504-3.
10
Binding of dexamethasone and cortisol to cytosol receptors in rat extensor digitorum longus and soleus muscles.
Exp Neurol. 1977 Nov;57(2):342-8. doi: 10.1016/0014-4886(77)90070-x.
引用本文的文献
1
Epidermal proliferation of nude mouse skin, pig skin, and pig skin grafts. Failure of nude mouse skin to respond to the tumor promoter 12-O-tetradecanoyl phorbol 13-acetate.裸鼠皮肤、猪皮肤及猪皮肤移植片的表皮增殖。裸鼠皮肤对肿瘤促进剂十四酰佛波醇乙酯无反应。
J Exp Med. 1980 Nov 1;152(5):1329-39. doi: 10.1084/jem.152.5.1329.
本文引用的文献
1
The stimulation of phospholipid metabolism in mouse skin following phorbol ester treatment.佛波酯处理后小鼠皮肤中磷脂代谢的刺激作用。
Biochim Biophys Acta. 1972 Sep 7;280(1):57-70. doi: 10.1016/0005-2760(72)90212-3.
2
Chemical carcinogenesis.化学致癌作用
N Engl J Med. 1971 Sep 23;285(13):721-34. doi: 10.1056/NEJM197109232851305.
3
Stimulation of the phosphorylation of mouse epidermal histones by tumor-promoting agents.肿瘤促进剂对小鼠表皮组蛋白磷酸化的刺激作用。
Cancer Res. 1973 Jan;33(1):134-9.
4
Phorbolesters--the irritants and cocarcinogens of Croton Tiglium L.佛波酯——巴豆的刺激物和促癌物
Fortschr Chem Org Naturst. 1974;31(0):377-467. doi: 10.1007/978-3-7091-7094-6_7.
5
6
7
Ultrastructural changes in the epidermis of mice induced by methylcholanthrene, croton oil and phorbol.
Arch Int Physiol Biochim. 1972 Aug;80(3):481-8. doi: 10.3109/13813457209075243.
8
9
On the molecular structure of receptors for co-carcinogens and some anti-cancer drugs.
Psychoneuroendocrinology. 1975;1(2):123-30. doi: 10.1016/0306-4530(75)90004-9.
10
Nonspecific inhibition of DNA repair by promoting and nonpromoting phorbol esters.
J Natl Cancer Inst. 1975 Oct;55(4):801-2. doi: 10.1093/jnci/55.4.801.
Zotero 插件