Khogali M
Br J Ind Med. 1969 Oct;26(4):308-13. doi: 10.1136/oem.26.4.308.
308-313. An epidemiological study in cotton ginneries in the Sudan covered 323 permanently employed ginnery workers, a random sample of 35 seasonal farfara workers, and a control group of 24 members of a fire brigade. All the workers studied were men. The study showed a prevalence of byssinosis (defined as chest tightness starting on return from the annual holiday and continuing for at least three consecutive days) in 20% of the ginnery workers and in 48·6% of the farfara workers. Workers exposed to dust showed a mean fall in F.E.V. of -0·10 litre during the shift, while workers not so exposed showed a mean rise of +0·23 litre; this difference was statistically significant. The F.E.V. was adjusted for age and standing height. The adjusted means of F.E.V. were significantly lower for workers exposed to dust compared with those in the control group. The workers with byssinosis showed a statistically significant fall in F.E.V. when compared with all ginnery workers; and a highly significant fall when compared with cotton workers without chest symptoms. An attempt was made to grade the byssinotics according to the extent of fall in F.E.V. during the shift. The concentration of fine dust (< 7 μ) was measured in each work place. There was a statistically significant association between the prevalence of byssinosis and the concentration of fine dust when comparing the ginnery and farfara workers. Also, there was a significant relationship between the mean adjusted F.E.V., the mean fall in F.E.V., and the fine dust concentration.
308 - 313。在苏丹轧棉厂开展的一项流行病学研究涵盖了323名长期受雇的轧棉厂工人、随机抽取的35名季节性法法拉工人样本以及一个由24名消防队队员组成的对照组。所有参与研究的工人均为男性。该研究表明,轧棉厂工人中棉尘肺患病率(定义为年假归来后开始出现且持续至少连续三天的胸闷)为20%,法法拉工人中患病率为48.6%。接触粉尘的工人在轮班期间第一秒用力呼气量(F.E.V.)平均下降0.10升,而未接触粉尘的工人平均上升0.23升;这种差异具有统计学意义。F.E.V.针对年龄和身高进行了调整。与对照组相比,接触粉尘的工人经调整后的F.E.V.均值显著更低。与所有轧棉厂工人相比,患有棉尘肺的工人F.E.V.出现了具有统计学意义的下降;与无胸部症状的棉花工人相比,下降极为显著。研究人员尝试根据轮班期间F.E.V.的下降程度对棉尘肺患者进行分级。在每个工作场所测量了细粉尘(<7微米)的浓度。比较轧棉厂和法法拉工人时,棉尘肺患病率与细粉尘浓度之间存在统计学意义的关联。此外,经调整后的F.E.V.均值、F.E.V.的平均下降值与细粉尘浓度之间存在显著关系。