[左旋咪唑，一种具有免疫刺激潜能的化学明确物质——综述]
[Levamisole, a chemically defined substance with immunostimulating potential--a review].
作者信息
Staber G F
出版信息
Fortschr Med. 1976 May 13;94(14):793-800.
In contrast to immunosuppression, immunostimulation is still at an early stage of development. Levamisole is the first chemically defined substance with immunostimulating potential which can be applied systemically. After a short consideration of the chemistry and pharmacology of Levamisole, its effect in different animal experimental models of humoral and cell-mediated immunity are discussed in detail. Moreover, the following review deals with the influence of Levamisole on several immunological parameters in man. Finally, the therapeutical results achieved up to now by different clinical indications are reported.
与免疫抑制相反，免疫刺激仍处于发展的早期阶段。左旋咪唑是第一种具有免疫刺激潜力的可全身应用的化学定义物质。在简要介绍左旋咪唑的化学和药理学之后，将详细讨论其在体液免疫和细胞介导免疫的不同动物实验模型中的作用。此外，以下综述涉及左旋咪唑对人体若干免疫学参数的影响。最后，报告了目前不同临床适应症所取得的治疗结果。
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