DuPont E, Jones C E, Luedecke R A, Smith E E
Circ Shock. 1979;6(4):323-31.
Using the tracer microsphere technique, the effect of circumflex artery ligation on regional myocardial perfusion was studied in 8 ventricles which had been sympathectomized 2 weeks earlier and in 9 nonsympathectomized controls. Preocclusion flow values in the chronically sympathectomized ventricles were approximately 75% of those in the controls even though heart rate and arterial pressure were maintained at the same levels in the 2 groups. After circumflex artery ligation, flow to the central ischemic region was slightly greater in the sympathectomized ventricle, but this difference was not statistically significant. However, in the ischemic region adjacent to the central ischemic region, flows in the chronically sympathectomized ventricle were 250--450% of those in the nonsympathectomized ventricle. When these flows were normalized to the preocclusion values, these differences were even greater. Thus, following circumflex artery occlusion, ischemic perfusion of the chronically sympathectomized myocardium is substantially improved.
采用示踪微球技术，在8个两周前已行交感神经切除术的心室以及9个未行交感神经切除术的对照心室中，研究了回旋支动脉结扎对局部心肌灌注的影响。尽管两组的心率和动脉压维持在相同水平，但慢性交感神经切除心室的闭塞前血流值约为对照组的75%。回旋支动脉结扎后，交感神经切除心室中流向中央缺血区域的血流略多，但这种差异无统计学意义。然而，在与中央缺血区域相邻的缺血区域，慢性交感神经切除心室中的血流是未行交感神经切除心室的250% - 450%。当这些血流根据闭塞前值进行标准化时，这些差异甚至更大。因此，在回旋支动脉闭塞后，慢性交感神经切除心肌的缺血灌注得到显著改善。
