A-去甲甾体类化合物作为仓鼠的性交后避孕药，特别涉及卵子的运输和退化。
A-nor steroids as post-coital contraceptives in the hamster with special reference to the transport and degeneration of eggs.
作者信息
Gu Z, Chang M C
出版信息
Contraception. 1979 Dec;20(6):549-57. doi: 10.1016/s0010-7824(79)80034-7.
PMID:535365
Abstract
Two A-nor steroids, Anordrin and H241, showed a marked antifertility effect when given orally to hamsters at 10 mg/kg/day for three or four days after mating. Further study indicated that the antifertility effect was due to a disturbance of egg transport, retarded development and degeneration of fertilized eggs.
摘要
两种去甲甾体化合物，双炔失碳酯和H241，在交配后以10毫克/千克/天的剂量给仓鼠口服三或四天时，显示出显著的抗生育作用。进一步的研究表明，这种抗生育作用是由于卵子运输紊乱、受精卵发育迟缓及退化所致。
Zotero 插件