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抗生育药物U11,100A和U11,555A在大鼠体内的作用机制

Mechanisms of action of the antifertility agents U11, 100A and U11,555A in the rat.

作者信息

Siddiqui U A, Heald P J

出版信息

J Reprod Fertil. 1976 Jul;47(2):251-4. doi: 10.1530/jrf.0.0470251.

Abstract

Mature female rats were given U11,555A and U11,100A on orally on Day 2 of pregnancy and the number of implantations counted on Day 9. Using doses which reduced the implantation number to approximately 40% that of the controls, it was shown that the reduced number was not due to an effect on egg transport or to a delay of implantation.

摘要

在妊娠第2天给成熟雌性大鼠口服U11,555A和U11,100A,并在第9天统计着床数。使用能使着床数降至对照组约40%的剂量,结果表明着床数减少并非由于对卵子运输的影响或着床延迟。

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