致倦库蚊中己糖激酶的遗传学
The genetics of hexokinase in a mosquito, Culex pipiens.
作者信息
Cheng M L, Hacker C S
出版信息
Genetics. 1979 Jul;92(3):903-13. doi: 10.1093/genetics/92.3.903.
Abstract
The genetics of hexokinase (HK) variants in a mosquito, Culex pipiens L., was studied using starch gel electrophoresis. Three isozymic forms of HK, all migrating anodally, were present in all three body regions, but in differing proportions. No obvious differences in specificity for three hexose sugars was detected among the three isozymic bands. However, qualitative differences in staining intensity indicate the following order of substrate affinity: glucose greater than fructose greater than mannose. The inheritance of the HK variants is controlled by a pair of co-dominant alleles at a single genetic locus.
摘要
利用淀粉凝胶电泳研究了致倦库蚊（Culex pipiens L.）中己糖激酶（HK）变体的遗传学。在其身体的三个部位均存在三种阳极迁移的HK同工酶形式，但比例不同。在这三条同工酶带中未检测到对三种己糖的特异性有明显差异。然而，染色强度的定性差异表明底物亲和力顺序如下：葡萄糖大于果糖大于甘露糖。HK变体的遗传由单个基因座上的一对共显性等位基因控制。
相似文献
1
The genetics of hexokinase in a mosquito, Culex pipiens.
Genetics. 1979 Jul;92(3):903-13. doi: 10.1093/genetics/92.3.903.
2
Genetic studies on hexokinase in the mosquito Aedes togoi.
Biochem Genet. 1987 Jun;25(5-6):375-84. doi: 10.1007/BF00554546.
3
Inheritance of 6-phosphogluconate dehydrogenase variants in Culex pipiens quinquefasciatus Say.
J Hered. 1976 Jul-Aug;67(4):215-9. doi: 10.1093/oxfordjournals.jhered.a108712.
4
Identification and linkage relationships of three hexokinase genes in Aedes aegypti.
Biochem Genet. 1978 Jun;16(5-6):571-5. doi: 10.1007/BF00484220.
5
Esterases in the mosquito Culex pipiens pipiens L: formal genetics and polymorphism of adult esterases.
Biochem Genet. 1976 Jun;14(5-6):481-93. doi: 10.1007/BF00486128.
6
Genetic similarity among Egyptian populations of Culex pipiens (Diptera: Culicidae).
J Med Entomol. 1991 Mar;28(2):198-204. doi: 10.1093/jmedent/28.2.198.
7
Genetic differentiation of Culex pipiens (Diptera: Culicidae) in China.
Bull Entomol Res. 2007 Jun;97(3):291-7. doi: 10.1017/S0007485307004968.
8
Molecular and biochemical characterization of Eimeria tenella hexokinase.
Parasitol Res. 2016 Sep;115(9):3425-33. doi: 10.1007/s00436-016-5104-4. Epub 2016 May 6.
9
Novel alleles of yeast hexokinase PII with distinct effects on catalytic activity and catabolite repression of SUC2.
Microbiology (Reading). 1999 Mar;145 ( Pt 3):703-714. doi: 10.1099/13500872-145-3-703.
10
Mig1 localization exhibits biphasic behavior which is controlled by both metabolic and regulatory roles of the sugar kinases.
Mol Genet Genomics. 2020 Nov;295(6):1489-1500. doi: 10.1007/s00438-020-01715-4. Epub 2020 Sep 19.
引用本文的文献
1
Isoenzymes related to flight activity in Tetragonisca angustula (Hymenoptera:Apidae:Meliponinae): evidence of postranslational modification of the hexokinase and detection of new glycerol-3-phosphate dehydrogenase variants.
Biochem Genet. 1995 Dec;33(11-12):365-75. doi: 10.1007/BF00554595.
2
Genetic control of hexokinase variation in insects.
Biochem Genet. 1982 Feb;20(1-2):47-57. doi: 10.1007/BF00484935.
3
Genetic studies on hexokinase in the mosquito Aedes togoi.
Biochem Genet. 1987 Jun;25(5-6):375-84. doi: 10.1007/BF00554546.
本文引用的文献
1
Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue.
Biochem J. 1955 Aug;60(4):604-17. doi: 10.1042/bj0600604.
2
Two or more electrophoretic zones from a single macromolecule.
Ann N Y Acad Sci. 1968 Jun 14;151(1):638-49. doi: 10.1111/j.1749-6632.1968.tb11924.x.
3
Enzymatically active conformers of mitochondrial malate dehydrogenase.
Proc Natl Acad Sci U S A. 1966 Aug;56(2):578-85. doi: 10.1073/pnas.56.2.578.
4
Studies on isozymes of hexokinase in animal tissues.
Ann N Y Acad Sci. 1968 Jun 14;151(1):332-50. doi: 10.1111/j.1749-6632.1968.tb11899.x.
5
Isozymes: classification, frequency, and significance.
Int Rev Cytol. 1969;25:297-332. doi: 10.1016/s0074-7696(08)60206-5.
6
Control of lysosomal acid phosphatase expression in man-mouse cell hybrids.
Biochem Genet. 1974 Feb;11(2):121-39. doi: 10.1007/BF00485769.
7
Tissue-specific glucose 6-phosphate dehydrogenases in anopheline mosquitoes.
J Histochem Cytochem. 1974 Apr;22(4):260-5. doi: 10.1177/22.4.260.
8
An electrophoretic study of the distribution and properties of human hexokinases.
Biochem Genet. 1975 Dec;13(11-12):857-66. doi: 10.1007/BF00484416.
9
The inheritance of pigmented-paddle (du2) in Culex pipiens (Diptera: Culicidae).
J Med Entomol. 1976 Dec 8;13(3):347-50. doi: 10.1093/jmedent/13.3.347.
10
Inheritance of 6-phosphogluconate dehydrogenase variants in Culex pipiens quinquefasciatus Say.
J Hered. 1976 Jul-Aug;67(4):215-9. doi: 10.1093/oxfordjournals.jhered.a108712.
Zotero 插件