De Stordeur E
Biochem Genet. 1976 Jun;14(5-6):481-93. doi: 10.1007/BF00486128.
The genetics of two esterase loci active in autogenous adults of the mosquito Culex pipiens pipiens L. has been studied by means of starch gel electrophoresis. Three alleles at the Est-1 locus and eight at the Est-2 locus are described. Both loci have a null allele. Active alleles are codominant and there is no hybrid enzyme in heterozygotes. The Est-1 locus codes esterases preferentially hydrolyzing alpha-naphthylacetate and the Est-2 locus esterases preferentially hydrolyzing beta-naphthylacetate. Strains homozygous for both loci were selected. Linkage studies of the two loci have shown that they are not sex linked but are linked to each other, the crossover frequency being 8.6%. The polymorphism of two laboratory and two natural populations is described for both loci. Phenotypic distributions are in good agreement with Hardy-Weinberg expectations.
利用淀粉凝胶电泳法，对致倦库蚊自育成虫中两个具有活性的酯酶基因座的遗传学进行了研究。描述了Est-1基因座的三个等位基因和Est-2基因座的八个等位基因。两个基因座均有一个无效等位基因。活性等位基因是共显性的，杂合子中不存在杂交酶。Est-1基因座编码的酯酶优先水解α-萘乙酸，Est-2基因座编码的酯酶优先水解β-萘乙酸。选择了两个基因座均为纯合的品系。对这两个基因座的连锁研究表明，它们不与性别连锁，但彼此连锁，交叉频率为8.6%。描述了两个实验室种群和两个自然种群在这两个基因座上的多态性。表型分布与哈迪-温伯格预期高度吻合。
