• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Tumor inhibitors. XLVII. Vernodalin and vernomygdin, two new cytotoxic sesquiterpene lactones from Vernonia amygdalina Del.

作者信息

Kupchan S M, Hemingway R J, Karim A, Werner D

出版信息

J Org Chem. 1969 Dec;34(12):3908-11. doi: 10.1021/jo01264a035.

DOI:10.1021/jo01264a035
PMID:5357533
Abstract
摘要

相似文献

1
Tumor inhibitors. XLVII. Vernodalin and vernomygdin, two new cytotoxic sesquiterpene lactones from Vernonia amygdalina Del.肿瘤抑制剂。XLVII。斑鸠菊内酯和斑鸠菊苦素,来自扁桃斑鸠菊的两种新型细胞毒性倍半萜内酯 。
J Org Chem. 1969 Dec;34(12):3908-11. doi: 10.1021/jo01264a035.
2
Tumor inhibitors. XLVI. Vernolepin, a novel sesquiterpene dilactone tumor inhibitor from Vernonia hymenolepis A. Rich.肿瘤抑制剂。XLVI. 斑鸠菊内酯,一种从膜苞斑鸠菊中提取的新型倍半萜双内酯肿瘤抑制剂。
J Org Chem. 1969 Dec;34(12):3903-7. doi: 10.1021/jo01264a034.
3
Tumor inhibitors. 48. Taxodione and taxodone, two novel diterpenoid quinone methide tumor inhibitors from Taxodium distichum.
J Org Chem. 1969 Dec;34(12):3912-8. doi: 10.1021/jo01264a036.
4
Desoxypodophyllotoxin, the cytotoxic principle of Callitris columellaris F. Muell.
J Pharm Sci. 1971 Jan;60(1):121-2. doi: 10.1002/jps.2600600125.
5
Tumor inhibitors XL. The isolation and structural elucidation of elephantin and elephantopin, two novel sesquiterpenoid tumor inhibitors from Elephantopus elatus.
J Org Chem. 1969 Dec;34(12):3867-75. doi: 10.1021/jo01264a028.
6
Tumor inhibitors. XLI. Structural elucidation of tumor-inhibitory sesquiterpene lactones from Eupatorium rotundifolium.
J Org Chem. 1969 Dec;34(12):3876-83. doi: 10.1021/jo01264a029.
7
Tumor inhibitors. XLIV. The isolation and characterization of hellebrigenin 3-acetate and hellebrigenin 3,5-diacetate, bufadienolide tumor inhibitors from Bersama abyssinica.
J Org Chem. 1969 Dec;34(12):3894-8. doi: 10.1021/jo01264a032.
8
Antitumor agents. I. Augustibalin, a new cytotoxic sesquiterpene lactone from Balduina angustifolia (Pursh.) Robins.
J Pharm Sci. 1972 Apr;61(4):626-8. doi: 10.1002/jps.2600610431.
9
Tumor inhibitors. LVI. Cucurbitacins O,P, and Q, the cytotoxic principles of Brandegea bigelovii.
J Org Chem. 1970 Sep;35(9):2891-4. doi: 10.1021/jo00834a007.
10
Tumor inhibitors. 43. Solapalmitine and solapalmitenine, two novel alkaloid tumor inhibitors from Solanum tripartitium.
J Org Chem. 1969 Dec;34(12):3888-93. doi: 10.1021/jo01264a031.

引用本文的文献

1
Vernodalin Triggers ROS-Mediated Apoptosis in TPC-1 Human PapillaryThyroid Cancer Cells Suppression of the MAPKs Signaling Pathway.Vernodalin 诱导 TPC-1 人甲状腺乳头状癌细胞中 ROS 介导的细胞凋亡 抑制 MAPKs 信号通路。
Comb Chem High Throughput Screen. 2024;27(14):2151-2158. doi: 10.2174/0113862073286226240220092357.
2
Synthesis and anticancer studies of Michael adducts and Heck arylation products of sesquiterpene lactones, zaluzanin D and zaluzanin C from .倍半萜内酯扎鲁扎宁 D 和扎鲁扎宁 C 的迈克尔加成物及赫克芳基化产物的合成与抗癌研究 来自于
RSC Adv. 2018 Nov 14;8(67):38289-38304. doi: 10.1039/c8ra06238b.
3
JAK2/STAT3‑mediated dose‑dependent cytostatic and cytotoxic effects of sesquiterpene lactones from on A549 human lung carcinoma cells.
JAK2/STAT3 介导的倍半萜内酯对 A549 人肺癌细胞的剂量依赖性细胞抑制和细胞毒性作用。
Oncol Rep. 2022 Jan;47(1). doi: 10.3892/or.2021.8217. Epub 2021 Nov 5.
4
A systematic review on COVID-19 pandemic with special emphasis on curative potentials of Nigeria based medicinal plants.一项关于新冠疫情的系统综述,特别强调尼日利亚药用植物的治疗潜力。
Heliyon. 2020 Sep;6(9):e04897. doi: 10.1016/j.heliyon.2020.e04897. Epub 2020 Sep 9.
5
Ethiopian Medicinal Plants Traditionally Used for the Treatment of Cancer, Part 2: A Review on Cytotoxic, Antiproliferative, and Antitumor Phytochemicals, and Future Perspective.传统上用于治疗癌症的埃塞俄比亚药用植物,第2部分:细胞毒性、抗增殖和抗肿瘤植物化学物质综述及未来展望。
Molecules. 2020 Sep 3;25(17):4032. doi: 10.3390/molecules25174032.
6
Vernodalol mediates antitumor effects in acute promyelocytic leukemia cells.韦诺洛尔在急性早幼粒细胞白血病细胞中发挥抗肿瘤作用。
Oncol Lett. 2018 Feb;15(2):2227-2235. doi: 10.3892/ol.2017.7544. Epub 2017 Dec 7.
7
Chemotherapeutic Vulnerability of Triple-negative Breast Cancer Cell-derived Tumors to Pretreatment with Vernonia amygdalina Aqueous Extracts.三阴乳腺癌细胞衍生肿瘤对斑鸠菊水提取物预处理的化疗易感性。
Anticancer Res. 2016 Aug;36(8):3933-43.
8
Recent perspectives on the anticancer properties of aqueous extracts of Nigerian .关于尼日利亚水提取物抗癌特性的最新观点。
Botanics. 2015;5:65-76. doi: 10.2147/BTAT.S62984. Epub 2015 Nov 30.
9
: Folk Medicine, Analysis, and Potential Application for Cancer Treatment.民间医学、分析及其在癌症治疗中的潜在应用
Curr Pharm Anal. 2008;4(1):20-24. doi: 10.2174/157341208783497579.
10
Ethnopharmacological Survey of Plants Used in the Traditional Treatment of Gastrointestinal Pain, Inflammation and Diarrhea in Africa: Future Perspectives for Integration into Modern Medicine.非洲用于治疗胃肠道疼痛、炎症和腹泻的传统植物的民族药理学调查:纳入现代医学的未来展望。
Animals (Basel). 2013 Mar 4;3(1):158-227. doi: 10.3390/ani3010158.