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民间医学、分析及其在癌症治疗中的潜在应用

: Folk Medicine, Analysis, and Potential Application for Cancer Treatment.

作者信息

Izevbigie Ernest B, Howard C B, Lee K S

机构信息

The Laboratory of Cellular Signaling, Phytoceuticals, Cancer Prevention and Therapies, Jackson State University, Jackson, MS 39217, USA; NIH-Center for Environmental Health, College of Science, Engineering and Technology, Jackson State University, Jackson, MS 39217, USA; Department of Biology, Jackson State University, Jackson, MS 39217, USA.

NIH-Center for Environmental Health, College of Science, Engineering and Technology, Jackson State University, Jackson, MS 39217, USA; Department of Biology, Jackson State University, Jackson, MS 39217, USA.

出版信息

Curr Pharm Anal. 2008;4(1):20-24. doi: 10.2174/157341208783497579.

Abstract

Folk medicine (FM) is practiced by people without access to conventional medical services; it usually involves the use of natural remedies such as herbs or vegetable substances. Before the use of pharmaceutical drugs, and surgical procedures, these healing methods were used, and are still in use today. It is estimated that twenty five percent of all therapeutic drugs trace their origins to plants, and almost two-thirds of the people of the world rely on their healing powers. One hundred years ago, health care in the U.S. was provided by a highly competitive medical sect, and quite infrequently, folk medicine practitioners were patronized. However, FM usage in the U.S. has increased drastically during the past decade. National surveys of adults (18 years of age or older) show that one in three adults use unconventional therapies or Complementary and Alternative Medicine (CAM) in the U.S. The rate of CAM usage is more than eighty percent among cancer patients. (VA) is well known for its medicinal importance. Fractionation of the VA extracts with solvents of varying polarities, by silica gels analyses, UV Spectrophotometer, HPLC, TLC and NMR techniques have yielded some biologically-active fractions.

摘要

民间医学(FM)由无法获得传统医疗服务的人施行;它通常涉及使用草药或植物性物质等天然疗法。在使用药物和外科手术之前,这些治疗方法就已被使用,并且至今仍在使用。据估计,所有治疗药物中有25%的起源可追溯到植物,世界上近三分之二的人依赖它们的治疗功效。一百年前,美国的医疗保健由竞争激烈的医学派别提供,民间医学从业者很少有人光顾。然而,在过去十年中,美国对民间医学的使用急剧增加。对成年人(18岁及以上)的全国性调查显示,美国三分之一的成年人使用非传统疗法或补充替代医学(CAM)。癌症患者中CAM的使用率超过80%。缬草(VA)因其药用价值而闻名。通过硅胶分析、紫外分光光度计、高效液相色谱、薄层色谱和核磁共振技术,用不同极性的溶剂对VA提取物进行分馏,得到了一些具有生物活性的馏分。

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