Richelle M
J Exp Anal Behav. 1969 Nov;12(6):989-98. doi: 10.1901/jeab.1969.12-989.
Cats trained under a fixed-interval 5-min schedule of milk presentation were injected with diazepam, amphetamine, and combinations of amphetamine and diazepam. Diazepam increased overall response rate as a function of the dose and disrupted the temporal pattern of responding. Low doses of amphetamine (0.5 mg/kg) usually increased the response rate; higher doses (1 to 2 mg/kg) either decreased the response rate or had little effect. Amphetamine always disrupted the temporal pattern of responding, even though it did not affect the overall rate. When doses of amphetamine that increased the response rate or left it unchanged were combined with diazepam, a potentiated increase in response rate occurred. When doses of amphetamine that decreased the response rate were combined with diazepam, the amphetamine-induced rate decreases were reversed at least partially. Less clear potentiation of disruption of the temporal pattern of responding was observed when amphetamine and diazepam were combined.
在固定间隔5分钟给予牛奶的训练方案下训练的猫，被注射了地西泮、苯丙胺以及苯丙胺和地西泮的组合。地西泮作为剂量的函数增加了总体反应率，并扰乱了反应的时间模式。低剂量的苯丙胺（0.5毫克/千克）通常会增加反应率；高剂量（1至2毫克/千克）要么降低反应率，要么影响很小。苯丙胺总是会扰乱反应的时间模式，即使它不影响总体反应率。当增加反应率或使其保持不变的苯丙胺剂量与地西泮联合使用时，反应率会出现增强的增加。当降低反应率的苯丙胺剂量与地西泮联合使用时，苯丙胺引起的反应率降低至少会部分逆转。当苯丙胺和地西泮联合使用时，观察到的反应时间模式扰乱的增强不太明显。
