Eddy J D, O'Brien E T, Singh S P
Br Med J. 1969 Dec 13;4(5684):663-5. doi: 10.1136/bmj.4.5684.663.
Glucagon was administered to six patients with acute myocardial infarction. Three of them had cardiogenic shock syndrome. Glucagon produced a positive inotropic response in all cases, which resulted in a significant rise in blood pressure, with only slight chronotropic effect. No arrhythmias were induced, and all patients with cardiogenic shock improved temporarily. Further evaluation of glucagon in shock syndrome to determine the dose and method of administration is required.
对6例急性心肌梗死患者使用了胰高血糖素。其中3例患有心源性休克综合征。胰高血糖素在所有病例中均产生了正性肌力反应,导致血压显著升高,而变时作用轻微。未诱发心律失常,所有心源性休克患者均暂时好转。需要进一步评估胰高血糖素在休克综合征中的作用,以确定给药剂量和方法。