Allison S P, Chamberlain M J, Hinton P
Br Med J. 1969 Dec 27;4(5686):776-8. doi: 10.1136/bmj.4.5686.776.
Glucose tolerance tests performed on 12 patients within 15 hours of myocardial infarction and repeated two to four weeks later showed failure of insulin secretion, hyperglycaemia, glucose intolerance, and high free fatty acid levels. More pronounced changes were found in patients with cardiogenic shock. These findings suggest that the therapeutic use of potassium, glucose, and insulin should be re-evaluated.
对12例心肌梗死后15小时内进行葡萄糖耐量试验,并在2至4周后重复试验,结果显示胰岛素分泌功能衰竭、高血糖、葡萄糖不耐受和游离脂肪酸水平升高。心源性休克患者的变化更为明显。这些发现提示,钾、葡萄糖和胰岛素的治疗用途应重新评估。