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阿狄森氏病和甲状旁腺功能减退症患者及其亲属血液中器官特异性抗体的家族分布情况。

Familial distributions of organ specific antibodies in the blood of patients with Addison's disease and hypoparathyroidism and their relatives.

作者信息

Spinner M W, Blizzard R M, Gibbs J, Abbey H, Childs B

出版信息

Clin Exp Immunol. 1969 Nov;5(5):461-8.

PMID:5360397
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1579139/
Abstract

Tests for antibodies against thyroid, adrenal and gastric tissues have been carried out on the blood of patients with Addison's disease with and without hypoparathyroidism and with hypoparathyroidism alone, their unaffected sibs, their parents, and a number of persons serving as controls. A previous study of the genetic and clinical characteristics of these patients and their families suggested a classification of the syndromes, some of which appear to be relatively homogenous as to origin, others not. The results of the antibody tests have been analysed in the context of the classification with results which support it and which do not suggest further heterogeneity.

摘要

已对患有或未患有甲状旁腺功能减退症的艾迪生病患者、仅患有甲状旁腺功能减退症的患者、他们未受影响的同胞、父母以及一些作为对照的人员的血液进行了针对甲状腺、肾上腺和胃组织抗体的检测。此前对这些患者及其家族的遗传和临床特征进行的一项研究提出了综合征的分类,其中一些综合征在起源方面似乎相对同质,另一些则不然。已在该分类的背景下分析了抗体检测结果,结果既支持该分类,也未表明存在进一步的异质性。

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1
Familial distributions of organ specific antibodies in the blood of patients with Addison's disease and hypoparathyroidism and their relatives.阿狄森氏病和甲状旁腺功能减退症患者及其亲属血液中器官特异性抗体的家族分布情况。
Clin Exp Immunol. 1969 Nov;5(5):461-8.
2
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Clinical and genetic heterogeneity in idiopathic Addison's disease and hypoparathyroidism.特发性 Addison 病和甲状旁腺功能减退症的临床及遗传异质性。
J Clin Endocrinol Metab. 1968 Jun;28(6):795-804. doi: 10.1210/jcem-28-6-795.
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引用本文的文献

1
Case report: Primary (autoimmune?) parathyroiditis.病例报告:原发性(自身免疫性?)甲状旁腺炎。
Virchows Arch A Pathol Pathol Anat. 1973 Nov 27;361(3):257-61. doi: 10.1007/BF00543989.
2
Hyperplastic proliferations of the ECL cells.嗜铬样细胞的增生性增殖。
Yale J Biol Med. 1992 Nov-Dec;65(6):805-25; discussion 827-9.

本文引用的文献

1
STUDIES OF THE ADRENAL ANTIGENS AND ANTIBODIES IN ADDISON'S DISEASE.艾迪生病中肾上腺抗原与抗体的研究。
J Clin Invest. 1963 Oct;42(10):1653-60. doi: 10.1172/JCI104851.
2
Maternal autoimmunization to thyroid as a probable cause of athyrotic cretinism.
N Engl J Med. 1960 Aug 18;263:327-36. doi: 10.1056/NEJM196008182630702.
3
Clinical and genetic heterogeneity in idiopathic Addison's disease and hypoparathyroidism.特发性 Addison 病和甲状旁腺功能减退症的临床及遗传异质性。
J Clin Endocrinol Metab. 1968 Jun;28(6):795-804. doi: 10.1210/jcem-28-6-795.
4
The incidence of parathyroid and other antibodies in the sera of patients with idiopathic hypoparathyroidism.特发性甲状旁腺功能减退症患者血清中甲状旁腺及其他抗体的发生率。
Clin Exp Immunol. 1966 Apr;1(2):119-28.