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尿液中安眠酮及其代谢物的检测。

Detection of methaqualone and its metabolites in urine.

作者信息

Burnett D, Goudie J H, Sherriff J M

出版信息

J Clin Pathol. 1969 Sep;22(5):602-4. doi: 10.1136/jcp.22.5.602.

DOI:10.1136/jcp.22.5.602
PMID:5364446
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC474264/
Abstract

A method is described for the detection of methaqualone and its metabolites in the presence of large doses of other drugs.

摘要

描述了一种在存在大剂量其他药物的情况下检测甲喹酮及其代谢物的方法。

相似文献

1
Detection of methaqualone and its metabolites in urine.尿液中安眠酮及其代谢物的检测。
J Clin Pathol. 1969 Sep;22(5):602-4. doi: 10.1136/jcp.22.5.602.
2
Mass screening and confirmation of methaqualone and its metabolites in urine by radioimmunoassay-thin-layer chromatography.采用放射免疫分析法-薄层色谱法对尿液中安眠酮及其代谢物进行大规模筛查与确证。
J Chromatogr. 1980 Mar 21;190(1):129-32. doi: 10.1016/s0021-9673(00)85519-3.
3
Simultaneous identification and quantitation of diphenhydramine and methaqualone.
Clin Toxicol. 1977 Sep;11(2):245-55. doi: 10.3109/15563657708989837.
4
Optimization of extraction and separation of narcotics from urine.尿液中麻醉药品提取与分离的优化。
Clin Biochem. 1974 Sep;7(3):280-9. doi: 10.1016/s0009-9120(74)92378-9.
5
Thin-layer chromatographic detection and identification of methaqualone metabolites in urine.尿液中安眠酮代谢物的薄层色谱检测与鉴定
Clin Chem. 1975 Jan;21(1):76-80.
6
Radioimmunoassay of methaqualone and its monohydroxy metabolites in urine.
Clin Chem. 1975 Dec;21(13):1878-81.
7
[Biotransformation of 2-methyl-3-o-tolyl-4(3H)-quinazolinone (Methaqualone). 3. Identification of 6-hydroxy-2-methyl-3-(3'-hydroxy-2'-methyl-phenyl)-4(3H)-quinazolinone as a renal elimination product of Methaqualone].
Arzneimittelforschung. 1970 Dec;20(12):1920-2.
8
Radioimmunoassay of methaqualone in human urine compared with chromatographic methods.人尿中安眠酮的放射免疫测定法与色谱法的比较
Clin Chem. 1978 Sep;24(9):1473-6.
9
Thin layer chromatographic screening for methaqualone, phenothiazines, opiates and benzodiazepines.对甲喹酮、吩噻嗪类、阿片类药物和苯二氮䓬类进行薄层色谱筛查。
J Clin Chem Clin Biochem. 1978 Feb;16(2):127-34. doi: 10.1515/cclm.1978.16.2.127.
10
Methaqualone overdose: analytical methodology, and the significance of serum drug concentrations.甲喹酮过量：分析方法及血清药物浓度的意义
Clin Chem. 1973 Jun;19(6):615-20.

本文引用的文献

1
STUDIES ON METABOLISM IN RAT AND MOUSE OF A NEW HYPNOTIC-METHAQUALONE.新型催眠药甲喹酮在大鼠和小鼠体内的代谢研究
Arch Int Pharmacodyn Ther. 1964 Mar 1;148:228-36.
2
Studies on metabolism of 2-methyl-3-o-tolyl-4(3H)-quinazolinone. I. The estimationof 2-methyl-3-o-toly-4(3H)-quinazolinone in biological materials.2-甲基-3-邻甲苯基-4(3H)-喹唑啉酮的代谢研究。I. 生物材料中2-甲基-3-邻甲苯基-4(3H)-喹唑啉酮的测定
Chem Pharm Bull (Tokyo). 1963 Jan;11:62-7. doi: 10.1248/cpb.11.62.
3
[On the detection of Revonal poisoning].[关于利眠宁中毒的检测]
Arch Toxikol. 1963;20:31-7.
4
Methaqualone addiction and delirium tremens.甲喹酮成瘾与震颤谵妄
Br Med J. 1967 Jul 8;3(5557):92-3. doi: 10.1136/bmj.3.5557.92.
5
A thin-layer chromatographic screening test for the detection of users of morphine or heroin.一种用于检测吗啡或海洛因使用者的薄层色谱筛查试验。
Am J Clin Pathol. 1966 Jul;46(1):58-62. doi: 10.1093/ajcp/46.1.58.
6
[On the biotransformation of 2-methyl-3-o-toly-4(3H)-quinazolinone (=methaqualone. 1. Analysis and isolation of renal excretory products as well as the identification of some metabolites].[关于2-甲基-3-邻甲苯基-4(3H)-喹唑啉酮（=甲喹酮）的生物转化。1. 肾脏排泄产物的分析、分离及某些代谢物的鉴定]
Arzneimittelforschung. 1966 Mar;16(3):395-401.