Rosen I B
Can Med Assoc J. 1969 Nov 29;101(11):45-51.
Confusion still prevails regarding the selection of patients with thyroid nodules for surgical treatment. Classical features of malignancy do not apply to growths of the thyroid gland. Duration, size, presence of calcification, scintiscanning and response to thyroid feeding are not, in themselves, reliable indicators of the absence or presence of malignancy. In 78 personal thyroidectomies there was a 60% overall neoplasm rate and a 25% malignancy rate. Operation is indicated for the thyroid lesion which is solitary, cold, unresponsive to thyroid feeding or accompanied by obvious evidence of malignancy. Recent experience indicates that thyroid surgery has a low morbidity and negligible mortality. Surgical treatment of the common forms of thyroid cancer yields excellent results if it is complete and is expertly done.
关于甲状腺结节患者手术治疗的选择，目前仍存在困惑。恶性肿瘤的典型特征并不适用于甲状腺肿物。病程、大小、钙化的存在、闪烁扫描以及甲状腺素喂养反应本身都不是判断有无恶性肿瘤的可靠指标。在78例个人甲状腺切除病例中，总体肿瘤发生率为60%，恶性肿瘤发生率为25%。对于孤立性、冷结节、对甲状腺素喂养无反应或伴有明显恶性证据的甲状腺病变，应考虑手术治疗。近期经验表明，甲状腺手术的发病率较低，死亡率可忽略不计。如果甲状腺癌的常见类型手术完整且操作熟练，其治疗效果极佳。
