Baldwin J N, Strickland R H, Cox M F
Appl Microbiol. 1969 Oct;18(4):628-30. doi: 10.1128/am.18.4.628-630.1969.
Eighty-three per cent of 200 different freshly isolated cultures of Staphylococcus epidermidis produced beta lactamase. Growth in the presence of acridine orange or ethidium bromide or growth at 44 C resulted in a high frequency of loss of the beta lactamase genes in some strains of S. epidermidis. The relationship between beta-lactamase production and resistance to mercuric, cadmium and arsenate ions differed from that observed in Staphylococcus aureus. It is postulated that the genes for beta lactamase in certain strains of S. epidermidis are on a plasmid.
200种不同的新鲜分离的表皮葡萄球菌培养物中,83%产生β-内酰胺酶。在吖啶橙或溴化乙锭存在下生长,或在44℃生长,导致某些表皮葡萄球菌菌株中β-内酰胺酶基因的高频丢失。表皮葡萄球菌中β-内酰胺酶产生与对汞、镉和砷酸盐离子的抗性之间的关系与在金黄色葡萄球菌中观察到的不同。据推测,某些表皮葡萄球菌菌株中的β-内酰胺酶基因位于质粒上。