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决定胃对2-脱氧-D-葡萄糖分泌反应的因素。

Factors which determine the gastric secretory response to 2-deoxy-D-glucose.

作者信息

Himsworth R L, Colin-Jones D G

出版信息

Gut. 1969 Dec;10(12):1015-9. doi: 10.1136/gut.10.12.1015.

Abstract

The physiological factors which determine the penetration of the brain by 2-deoxy-D-glucose have been studied and the practical importance of the blood-brain barrier has been demonstrated. The evaluation of the gastric secretory response to 2-deoxy-D-glucose has been shown to depend upon the plasma glucose concentration. It is concluded that because of the hazards and uncertainties in the use of 2-deoxy-D-glucose in man its use is to be deprecated.

摘要

已对决定2-脱氧-D-葡萄糖进入大脑的生理因素进行了研究,并证明了血脑屏障的实际重要性。已表明对2-脱氧-D-葡萄糖的胃分泌反应评估取决于血浆葡萄糖浓度。得出的结论是,由于在人体中使用2-脱氧-D-葡萄糖存在风险和不确定性,因此不提倡使用。

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Compensatory reactions to a lack of metabolizable glucose.对缺乏可代谢葡萄糖的代偿反应。
J Physiol. 1968 Sep;198(2):451-65. doi: 10.1113/jphysiol.1968.sp008616.

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