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新加坡不同种族中葡萄糖-6-磷酸脱氢酶缺乏症与糖尿病的关联。

Association of glucose-6-phosphate dehydrogenase deficiency with diabetes mellitus in ethnic groups of Singapore.

作者信息

Saha N

出版信息

J Med Genet. 1979 Dec;16(6):431-4. doi: 10.1136/jmg.16.6.431.

Abstract

Six hundred and nine male patients suffering from maturity onset diabetes mellitus, comprising 422 Chinese, 66 Malays, and 121 Indians, were investigated to determine the incidence of G6PD deficiency, ABO blood groups, and haemoglobin types, and these were compared with normal healthy controls. A positive association with a higher incidence of G6PD deficiency in diabetics was observed in Chinese and Indian patients. There was no significant difference in the frequencies of ABO blood groups and haemoglobin types between the patients and the controls in any of the ethnic groups studied.

摘要

对609例成年起病型糖尿病男性患者进行了调查,以确定葡萄糖-6-磷酸脱氢酶(G6PD)缺乏症、ABO血型和血红蛋白类型的发生率,并将这些结果与正常健康对照进行比较。其中包括422名中国人、66名马来人和121名印度人。在中国和印度患者中,观察到糖尿病患者中G6PD缺乏症的发生率呈正相关。在所研究的任何种族群体中,患者与对照组之间的ABO血型和血红蛋白类型频率均无显著差异。

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