口蹄疫病毒温度敏感突变体的物理和代谢特性的进一步研究。
Further studies of the physical and metabolic properties of foot-and-mouth disease virus temperature-sensitive mutants.
作者信息
Richmond J Y, Polatnick J
出版信息
Infect Immun. 1976 May;13(5):1392-6. doi: 10.1128/iai.13.5.1392-1396.1976.
Abstract
Three temperature-sensitive (ts) mutants of foot-and-mouth disease virus were classified as ribonucleic acid negative and as belonging to the same complementation group when measured by virus yields and [3H] uridine incorporation in paired, mixed infections at the nonpermissive temperature (38.5C). Mutant ts-22, the only mutant able to produce plaques at 38.5 C, was more sensitive to acid than were the parental wild-type or other mutant viruses. Diethylaminoethyl-dextran did not enhance the plaque-forming ability of the mutant viruses at 38.5C. All of the viruses inhibited host cell protein syntehsis at both permissive (33C) and nonpermissive (38.5C) temperatures.
摘要
当在非允许温度（38.5℃）下通过病毒产量以及在成对混合感染中[3H]尿苷掺入量来测定时，口蹄疫病毒的三个温度敏感（ts）突变体被归类为核糖核酸阴性且属于同一互补群。突变体ts - 22是唯一能够在38.5℃产生蚀斑的突变体，它比亲本野生型或其他突变病毒对酸更敏感。二乙氨基乙基葡聚糖在38.5℃时并未增强突变病毒的蚀斑形成能力。所有病毒在允许温度（33℃）和非允许温度（38.5℃）下均抑制宿主细胞蛋白质合成。
相似文献
1
Further studies of the physical and metabolic properties of foot-and-mouth disease virus temperature-sensitive mutants.
Infect Immun. 1976 May;13(5):1392-6. doi: 10.1128/iai.13.5.1392-1396.1976.
2
Viral interference phenomena induced by foot-and-mouth disease temperature-sensitive mutants in bovine kidney cells.
Arch Virol. 1979;61(1-2):105-14. doi: 10.1007/BF01320595.
3
Partial characterization of temperature-sensitive mutants of foot-and-mouth disease virus, O1 caseros strain.
Intervirology. 1982;18(3):128-34. doi: 10.1159/000149315.
4
Temperature-sensitive mutants of vesicular stomatitis virus: synthesis of virus-specific proteins.
J Virol. 1971 May;7(5):651-62. doi: 10.1128/JVI.7.5.651-662.1971.
5
Mapping of RNA- temperature-sensitive mutants of Sindbis virus: complementation group F mutants have lesions in nsP4.
J Virol. 1989 Mar;63(3):1194-202. doi: 10.1128/JVI.63.3.1194-1202.1989.
6
Dependence of RNA replication on continuous protein synthesis in a temperature-sensitive mutant of foot-and-mouth disease virus.
J Gen Virol. 1974 Oct;25(1):157-61. doi: 10.1099/0022-1317-25-1-157.
7
Production, isolation, and partial characterization of three foot-and-mouth disease virus temperature-sensitive mutants.
Infect Immun. 1975 Jun;11(6):1291-5. doi: 10.1128/iai.11.6.1291-1295.1975.
8
In vivo transcription and protein synthesis capabilities of bunyaviruses: wild-type snowshoe hare virus and its temperature-sensitive group I, group II, and group I/II mutants.
J Virol. 1979 Aug;31(2):426-36. doi: 10.1128/JVI.31.2.426-436.1979.
9
Temperature-sensitive mutants of Sindbis virus: biochemical correlates of complementation.
J Virol. 1967 Oct;1(5):956-62. doi: 10.1128/JVI.1.5.956-962.1967.
10
RNA synthesis by Newcastle disease virus temperature-sensitive mutants in two RNA-negative complementation groups.
J Virol. 1982 Jun;42(3):996-1006. doi: 10.1128/JVI.42.3.996-1006.1982.
引用本文的文献
1
Characterization of a foot-and-mouth disease mutant temperature-sensitive for viral RNA synthesis.
Arch Virol. 1980;63(3-4):191-201. doi: 10.1007/BF01315026.
2
Microassay for interferon, using [3H]uridine, microculture plates, and a multiple automated sample harvester.
Appl Environ Microbiol. 1980 Apr;39(4):823-7. doi: 10.1128/aem.39.4.823-827.1980.
3
Viral interference phenomena induced by foot-and-mouth disease temperature-sensitive mutants in bovine kidney cells.
Arch Virol. 1979;61(1-2):105-14. doi: 10.1007/BF01320595.
4
Evidence for a mouse pathogenicity locus in certain temperature-sensitive mutants of foot-and-mouth disease virus.
Infect Immun. 1977 Jun;16(3):827-31. doi: 10.1128/iai.16.3.827-831.1977.
本文引用的文献
1
Factors affecting the formation of plaques by the virus of foot-and-mouth disease on pig kidney monolayer tissue cultures.
Arch Gesamte Virusforsch. 1960;9:594-605. doi: 10.1007/BF01242146.
2
Kinetics of cell infection and penetration by the virus of foot-and-mouth disease.
J Bacteriol. 1962 Nov;84(5):929-42. doi: 10.1128/jb.84.5.929-942.1962.
3
Alteration plaque morphology of EMC virus with polycations.
Virology. 1961 Aug;14:502-4. doi: 10.1016/0042-6822(61)90349-x.
4
A plaque assay for foot-and-mouth disease virus and kinetics of virus reproduction.
Virology. 1957 Oct;4(2):224-36. doi: 10.1016/0042-6822(57)90060-0.
5
Inactivation of foot-and-mouth disease virus by pH and temperature changes and by formaldehyde.
Proc Soc Exp Biol Med. 1957 May;95(1):147-52. doi: 10.3181/00379727-95-23148.
6
Complementation between temperature-sensitive mutants of Sindbis virus.
Virology. 1966 Oct;30(2):214-23. doi: 10.1016/0042-6822(66)90097-3.
7
Plaque mutants of animal viruses.
Prog Med Virol. 1966;8:314-48.
8
Isolation and partial characterization of temperature-sensitive mutants of the SAT-1 strain of foot-and-mouth disease virus.
Isr J Med Sci. 1973 Feb;9(2):145-9.
9
Immunochemical studies of foot-and-mouth disease. VII. Characterization of foot-and-mouth disease virus concentrated by polyethylene glycol precipitation.
Arch Gesamte Virusforsch. 1970;30(4):343-52. doi: 10.1007/BF01258364.
10
The effect of diethylaminoethyl dextran and agar overlay pH on plaque formation by two plaque-size variants of foot-and-mouth disease virus.
Can J Comp Med. 1970 Jan;34(1):13-9.
Zotero 插件