Kamio A, Taguchi T, Shiraishi M, Shitama K, Takebayashi S, Cleveland J C, Kummerow F A
Paroi Arterielle. 1979 Oct;5(3):125-36.
Aortic specimens from 111 autopsy and 23 surgical cases were examined by light and electron microscopy. Differential mast cell counts were made of three aortic segments (ascending, thoracic, and abdominal) and layers (intimal, medial, adventitial). The mast cell counts varied considerably from case to case and sector to sector and generally showed no correlation with age, sex, or atherosclerotic severity. However, intimal mast cells were fewer in number in areas of lipid accumulation than in areas of diffuse intimal thickening without lipid accumulation. The reduction in the number of intimal mast cells may play a part in the localization of atherosclerosis.
对111例尸检和23例手术病例的主动脉标本进行了光镜和电镜检查。对主动脉的三个节段（升主动脉、胸主动脉和腹主动脉）和各层（内膜、中膜、外膜）进行了肥大细胞差异计数。肥大细胞计数在不同病例和不同节段差异很大，且一般与年龄、性别或动脉粥样硬化严重程度无关。然而，脂质积聚区域的内膜肥大细胞数量比无脂质积聚的弥漫性内膜增厚区域少。内膜肥大细胞数量的减少可能在动脉粥样硬化的定位中起作用。
