达那唑在性早熟治疗中的作用。
The role of danazol in the management of precocious puberty.
作者信息
Smith C S, Harris F
出版信息
Postgrad Med J. 1979;55 Suppl 5:81-6.
PMID:537954
Abstract
The management, investigation and treatment of 12 children with precocious puberty is described. Danazol, a synthetic derivative of ethisterone, has been used over a period of 3 1/2 years. Its clinical, endocrine and biochemical effects have been evaluated. Danazol ha a very useful clinical effect in controlling the development of secondary sexual features but does not modify the rapid linear growth and skeletal maturity seen in this condition.
摘要
本文描述了对12例性早熟儿童的管理、调查和治疗情况。炔羟雄烯异恶唑，一种炔孕酮的合成衍生物，已使用了3年半的时间。对其临床、内分泌和生化效应进行了评估。炔羟雄烯异恶唑在控制性征发育方面具有非常有用的临床效果，但不能改变这种情况下出现的快速线性生长和骨骼成熟。
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